PMID- 28189942 OWN - NLM STAT- MEDLINE DCOM- 20171127 LR - 20190318 IS - 1872-7123 (Electronic) IS - 0165-1781 (Linking) VI - 251 DP - 2017 May TI - Functional impairment and cognitive performance in mood disorders: A community sample of young adults. PG - 85-89 LID - S0165-1781(16)30703-X [pii] LID - 10.1016/j.psychres.2017.01.069 [doi] AB - The aim of this study was to compare the global functioning and cognitive performance in a community sample of young adults with mood disorders versus community controls. This was a cross-sectional study nested in a cohort study with a community sample. Data was collected from February 2012 to June 2014; specifically, at a mean of five years after the first phase, all young adults were invited to participate in a re-evaluation. Mini International Neuropsychiatric Interview - PLUS (MINI-PLUS) was used for the diagnosis of mood disorders. The Functional Assessment Short Test (FAST) and the Montreal Cognitive Assessment (MoCA) were used to assess the global functioning, and cognitive performance, respectively. Were included 1258 subjects. Functional impairment was greater in subjects with bipolar disorder when compared to community controls, and there were no differences between major depressive disorder and community controls. There were no significant differences in cognitive performance between young adults with mood disorders when compared to community controls. Functional impairment is a marker for bipolar disorder in young adults; however, gross cognitive impairment assessed by a screening test is not, possibly because cognition is impaired in more advanced stages of the disorder. CI - Copyright (c) 2017 Elsevier Ireland Ltd. All rights reserved. FAU - Reyes, Amanda N AU - Reyes AN AD - Universidade Catolica de Pelotas - Programa de Pos-Graduacao em Saude e Comportamento, Brazil. FAU - Cardoso, Taiane A AU - Cardoso TA AD - Laboratorio de Psiquiatria Molecular, Hospital de Clinicas de Porto Alegre; Universidade Federal do Rio Grande do Sul - Programa de Pos-Graduacao em Ciencias Medicas, Psiquiatria, Brazil. FAU - Jansen, Karen AU - Jansen K AD - Universidade Catolica de Pelotas - Programa de Pos-Graduacao em Saude e Comportamento, Brazil. FAU - Mondin, Thaise C AU - Mondin TC AD - Universidade Catolica de Pelotas - Programa de Pos-Graduacao em Saude e Comportamento, Brazil. FAU - Souza, Luciano D M AU - Souza LDM AD - Universidade Catolica de Pelotas - Programa de Pos-Graduacao em Saude e Comportamento, Brazil. FAU - Magalhaes, Pedro V S AU - Magalhaes PVS AD - Laboratorio de Psiquiatria Molecular, Hospital de Clinicas de Porto Alegre; Universidade Federal do Rio Grande do Sul - Programa de Pos-Graduacao em Ciencias Medicas, Psiquiatria, Brazil. FAU - Kapczinski, Flavio AU - Kapczinski F AD - Laboratorio de Psiquiatria Molecular, Hospital de Clinicas de Porto Alegre; Universidade Federal do Rio Grande do Sul - Programa de Pos-Graduacao em Ciencias Medicas, Psiquiatria, Brazil. FAU - Silva, Ricardo A AU - Silva RA AD - Universidade Catolica de Pelotas - Programa de Pos-Graduacao em Saude e Comportamento, Brazil. Electronic address: ricardo.as@uol.com.br. LA - eng PT - Journal Article DEP - 20170124 PL - Ireland TA - Psychiatry Res JT - Psychiatry research JID - 7911385 SB - IM MH - Adolescent MH - Adult MH - Brazil/epidemiology MH - Cognition/physiology MH - Cognition Disorders/diagnosis/*epidemiology/*psychology MH - Cohort Studies MH - Cross-Sectional Studies MH - Female MH - Humans MH - Male MH - Mood Disorders/diagnosis/*epidemiology/*psychology MH - Neuropsychological Tests MH - *Residence Characteristics MH - Young Adult OTO - NOTNLM OT - *Bipolar disorder OT - *Cognitive performance OT - *Current major depressive episode OT - *Functional impairment OT - *Mood disorders EDAT- 2017/02/13 06:00 MHDA- 2017/11/29 06:00 CRDT- 2017/02/13 06:00 PHST- 2016/04/22 00:00 [received] PHST- 2016/11/23 00:00 [revised] PHST- 2017/01/24 00:00 [accepted] PHST- 2017/02/13 06:00 [pubmed] PHST- 2017/11/29 06:00 [medline] PHST- 2017/02/13 06:00 [entrez] AID - S0165-1781(16)30703-X [pii] AID - 10.1016/j.psychres.2017.01.069 [doi] PST - ppublish SO - Psychiatry Res. 2017 May;251:85-89. doi: 10.1016/j.psychres.2017.01.069. Epub 2017 Jan 24.