PMID- 28191514
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220321
IS  - 2450-131X (Print)
IS  - 2224-4018 (Electronic)
IS  - 2224-4018 (Linking)
VI  - 4
IP  - 1
DP  - 2016 Apr 1
TI  - Anticoagulant therapy for non-ST-segment elevation acute coronary syndrome in 
      China: A multi-center observational study.
PG  - 25-28
LID - 10.1515/jtim-2016-0006 [doi]
AB  - OBJECTIVE: To assess the anticoagulant therapy for non-ST-segment elevation acute 
      coronary syndrome (NSTE-ACS) in China and to offer the rationale for establishing 
      reasonable strategies to improve the prognosis of NSTE-ACS. METHODS: A total of 
      1,502 patients with NSTE-ACS were recruited from 28 third-grade hospitals 
      distributed in 14 provinces and cities in China from December 2009 to December 
      2011. The strategies for diagnosis and treatment, decided by each hospital 
      respectively, were used for further analysis and comparison of medication, 
      percutaneous coronary intervention (PCI), and end points for efficacy and safety 
      assessment at 9 and 30 days following PCI. RESULTS: A lower incidence rate (P < 
      0.05) was noted for efficacy and safety in patients with unstable angina (UA) 
      than those with non-ST-segment elevation myocardial infarction (NSTE-MI). The 
      prescription rate of unfractionated heparin (UFH), low-molecular-weight heparin 
      (LMWH), fondaparinux, PCI, and single medication was 0.61%, 66.42%, 30.61%, 
      69.64%, and 70.74%, respectively. CONCLUSION: Compared with NSTE-MI, UA is 
      featured with better prognosis, less severity, and different outcome. However, in 
      clinical practice, the therapies for NSTE-MI and UA show no differences, which 
      deserves great attention. In China, the most common anticoagulant therapies for 
      NSTE-ACS are single medication, mainly based on LMWH and PCI.
FAU - Gong, Xiao-Huan
AU  - Gong XH
AD  - Key Laboratory of Public Health Safety, Ministry of Education, Centre for 
      Clinical Epidemiology, School of Public Health, Fudan University, Shanghai 
      200032, China.
FAU - Yu, Jin-Ming
AU  - Yu JM
AD  - Key Laboratory of Public Health Safety, Ministry of Education, Centre for 
      Clinical Epidemiology, School of Public Health, Fudan University, Shanghai 
      200032, China.
FAU - Mao, Yong
AU  - Mao Y
AD  - Key Laboratory of Public Health Safety, Ministry of Education, Centre for 
      Clinical Epidemiology, School of Public Health, Fudan University, Shanghai 
      200032, China.
FAU - Hu, Da-Yi
AU  - Hu DY
AD  - Heart Center, Peking University People's Hospital, Peking 100044, China.
LA  - eng
PT  - Journal Article
DEP - 20160414
PL  - Poland
TA  - J Transl Int Med
JT  - Journal of translational internal medicine
JID - 101673826
PMC - PMC5290911
OTO - NOTNLM
OT  - ST-segment elevation
OT  - acute coronary syndrome
OT  - anticoagulant
OT  - myocardial infarction
OT  - unstable angina
COIS- Conflicts of Interest: None declared.
EDAT- 2017/02/14 06:00
MHDA- 2017/02/14 06:01
PMCR- 2016/04/01
CRDT- 2017/02/14 06:00
PHST- 2017/02/14 06:00 [entrez]
PHST- 2017/02/14 06:00 [pubmed]
PHST- 2017/02/14 06:01 [medline]
PHST- 2016/04/01 00:00 [pmc-release]
AID - jtim-2016-0006 [pii]
AID - 10.1515/jtim-2016-0006 [doi]
PST - ppublish
SO  - J Transl Int Med. 2016 Apr 1;4(1):25-28. doi: 10.1515/jtim-2016-0006. Epub 2016 
      Apr 14.