PMID- 28205123
OWN - NLM
STAT- MEDLINE
DCOM- 20171201
LR  - 20240213
IS  - 1873-4626 (Electronic)
IS  - 1091-255X (Linking)
VI  - 21
IP  - 4
DP  - 2017 Apr
TI  - Isolated Pancreatic Uncinate Duct IPMN.
PG  - 744-745
LID - 10.1007/s11605-017-3380-7 [doi]
AB  - The ventral pancreas originally forms as an evagination of the common bile duct 
      at 32 days gestation and its duct, the uncinate duct, eventually rotates with the 
      ventral anlage to join the dorsal pancreas and fuse with the main pancreatic 
      duct. Thus, though often considered a "branch" duct of the pancreas, 
      embryologically, the uncinate duct is the "main" pancreatic duct of the ventral 
      pancreas. This concept is not fully addressed in the current definitions of 
      intraductal papillary mucinous neoplasms of the pancreas (IPMN) where 
      international consensus guidelines consider the main-duct IPMN as high risk for 
      malignancy and most small branch-duct IPMN as low risk for malignancy. Thus, it 
      is important to recognize that isolated uncinate-duct IPMN can occur and, based 
      on its embryologic origin and increased association with high-grade dysplasia and 
      invasive cancer, may be managed conceptually as a main duct type of disease 
      rather than a branch duct until better biomarkers of malignancy are discovered. 
      The images provide an example of this unique disease process.
FAU - Maker, Ajay V
AU  - Maker AV
AD  - Department of Surgery, Division of Surgical Oncology, University of Illinois at 
      Chicago, Chicago, IL, USA. amaker@uic.edu.
AD  - Department of Surgery, Creticos Cancer Center at Advocate Illinois Masonic 
      Medical Center, Chicago, IL, USA. amaker@uic.edu.
FAU - Maker, Vijay K
AU  - Maker VK
AD  - Department of Surgery, Division of Surgical Oncology, University of Illinois at 
      Chicago, Chicago, IL, USA.
AD  - Department of Surgery, Creticos Cancer Center at Advocate Illinois Masonic 
      Medical Center, Chicago, IL, USA.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20170215
PL  - Netherlands
TA  - J Gastrointest Surg
JT  - Journal of gastrointestinal surgery : official journal of the Society for Surgery 
      of the Alimentary Tract
JID - 9706084
SB  - IM
MH  - Aged
MH  - Humans
MH  - Imaging, Three-Dimensional
MH  - Male
MH  - Neoplasms, Cystic, Mucinous, and Serous/*diagnostic imaging/surgery
MH  - Pancreatic Ducts/*diagnostic imaging/embryology
MH  - Pancreatic Neoplasms/*diagnostic imaging/surgery
MH  - Tomography, X-Ray Computed
OTO - NOTNLM
OT  - Branch duct
OT  - IPMN
OT  - Intraductal papillary mucinous neoplasm
OT  - Main duct
OT  - Pancreas
OT  - Pancreas cancer
OT  - Uncinate
EDAT- 2017/02/17 06:00
MHDA- 2017/12/02 06:00
CRDT- 2017/02/17 06:00
PHST- 2017/01/21 00:00 [received]
PHST- 2017/01/27 00:00 [accepted]
PHST- 2017/02/17 06:00 [pubmed]
PHST- 2017/12/02 06:00 [medline]
PHST- 2017/02/17 06:00 [entrez]
AID - S1091-255X(23)02627-6 [pii]
AID - 10.1007/s11605-017-3380-7 [doi]
PST - ppublish
SO  - J Gastrointest Surg. 2017 Apr;21(4):744-745. doi: 10.1007/s11605-017-3380-7. Epub 
      2017 Feb 15.