PMID- 28208207 OWN - NLM STAT- MEDLINE DCOM- 20190610 LR - 20190613 IS - 1439-4421 (Electronic) IS - 0941-3790 (Linking) VI - 80 IP - S 02 DP - 2018 Mar TI - [Spatial Distribution of Type 2 Diabetes Mellitus in Berlin: Application of a Geographically Weighted Regression Analysis to Identify Location-Specific Risk Groups]. PG - S64-S70 LID - 10.1055/s-0042-123845 [doi] AB - Understanding which population groups in which locations are at higher risk for type 2 diabetes mellitus (T2DM) allows efficient and cost-effective interventions targeting these risk-populations in great need in specific locations. The goal of this study was to analyze the spatial distribution of T2DM and to identify the location-specific, population-based risk factors using global and local spatial regression models. To display the spatial heterogeneity of T2DM, bivariate kernel density estimation was applied. An ordinary least squares regression model (OLS) was applied to identify population-based risk factors of T2DM. A geographically weighted regression model (GWR) was then constructed to analyze the spatially varying association between the identified risk factors and T2DM. T2DM is especially concentrated in the east and outskirts of Berlin. The OLS model identified proportions of persons aged 80 and older, persons without migration background, long-term unemployment, households with children and a negative association with single-parenting households as socio-demographic risk groups. The results of the GWR model point out important local variations of the strength of association between the identified risk factors and T2DM. The risk factors for T2DM depend largely on the socio-demographic composition of the neighborhoods in Berlin and highlight that a one-size-fits-all approach is not appropriate for the prevention of T2DM. Future prevention strategies should be tailored to target location-specific risk-groups. CI - (c) Georg Thieme Verlag KG Stuttgart . New York. FAU - Kauhl, Boris AU - Kauhl B AD - Arztliche Versorgung, AOK Nordost, Potsdam. FAU - Pieper, Jonas AU - Pieper J AD - Fachbereich Bauingenieur- und Geoinformationswesen, Beuth Hochschule fur Technik Berlin, Berlin. FAU - Schweikart, Jurgen AU - Schweikart J AD - Fachbereich III, Beuth Hochschule fur Technik Berlin, Berlin. FAU - Keste, Andrea AU - Keste A AD - Arztliche Versorgung, AOK Nordost, Potsdam. FAU - Moskwyn, Marita AU - Moskwyn M AD - Arztliche Versorgung, AOK Nordost, Potsdam. LA - ger PT - Journal Article TT - Die raumliche Verbreitung des Typ 2 Diabetes Mellitus in Berlin - Die Anwendung einer geografisch gewichteten Regressionsanalyse zur Identifikation ortsspezifischer Risikogruppen. DEP - 20170216 PL - Germany TA - Gesundheitswesen JT - Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)) JID - 9204210 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Berlin MH - Child MH - *Diabetes Mellitus, Type 2/epidemiology MH - *Geographic Information Systems MH - Germany/epidemiology MH - Humans MH - Middle Aged MH - Regression Analysis MH - Risk Factors MH - Spatial Analysis MH - *Spatial Regression COIS- Die Autoren geben an, dass kein Interessenkonflikt besteht. EDAT- 2017/02/17 06:00 MHDA- 2019/06/14 06:00 CRDT- 2017/02/17 06:00 PHST- 2017/02/17 06:00 [pubmed] PHST- 2019/06/14 06:00 [medline] PHST- 2017/02/17 06:00 [entrez] AID - 10.1055/s-0042-123845 [doi] PST - ppublish SO - Gesundheitswesen. 2018 Mar;80(S 02):S64-S70. doi: 10.1055/s-0042-123845. Epub 2017 Feb 16.