PMID- 28208276
OWN - NLM
STAT- MEDLINE
DCOM- 20190218
LR  - 20190219
IS  - 1520-6882 (Electronic)
IS  - 0003-2700 (Linking)
VI  - 89
IP  - 3
DP  - 2017 Feb 7
TI  - Single-Drop Solution Electrode Discharge-Induced Cold Vapor Generation Coupling 
      to Matrix Solid-Phase Dispersion: A Robust Approach for Sensitive Quantification 
      of Total Mercury Distribution in Fish.
PG  - 2093-2100
LID - 10.1021/acs.analchem.6b04753 [doi]
AB  - Sensitive quantification of mercury distribution in fish is challenging because 
      of insufficient sensitivities of conventional analytical methods, the limited 
      mass of organs (tens of micrograms to several milligrams), and dilution of 
      analyte concentration from sample digestion. In this work, a simple and robust 
      approach coupling multiwall carbon nanotubes assisted matrix solid-phase 
      dispersion (MWCNTs-MSPD) to single-drop solution electrode glow discharge-induced 
      cold vapor generation (SD-SEGD-CVG) was developed for the sensitive determination 
      of mercury in limited amount of sample. Mercury species contained in a limited 
      amount of sample can be efficiently extracted into a 100 muL of eluent by 
      MWCNTs-MSPD, which are conveniently converted to Hg(0) by SD-SEGD-CVG and further 
      transported to atomic fluorescence spectrometry for their determination. 
      Therefore, analyte dilution resulted from sample preparation is avoided and 
      sensitivity is significantly improved. On the basis of consumption of 1 mg of 
      sample, a limit of detection of 0.01 mug L(-1) (0.2 pg) was obtained with relative 
      standard deviations (RSDs) of 5.2% and 4.6% for 2 and 20 mug L(-1), respectively. 
      The accuracy of the proposed method was validated by analysis of three Certified 
      Reference Materials with satisfying results. To confirm that SD-SEGD-CVG-AFS 
      coupling to MWCNTs-MSPD is a promising method to quantify mercury distribution in 
      fish, this method was successfully applied for the sensitive determination of 
      mercury in seven organs of common carps (muscle, gill, intestine, liver, 
      gallbladder, brain, and eye) after dietary of mercury species. The proposed 
      method provides advantages of minimum sample dilution, low blank, high sample 
      introduction efficiency, high sensitivity, and minimum toxic chemicals and sample 
      consumption.
FAU - Chen, Qian
AU  - Chen Q
AD  - Key Laboratory of Green Chemistry & Technology of MOE, College of Chemistry, 
      Sichuan University , Chengdu, Sichuan 610064, China.
FAU - Lin, Yao
AU  - Lin Y
AD  - Key Laboratory of Green Chemistry & Technology of MOE, College of Chemistry, 
      Sichuan University , Chengdu, Sichuan 610064, China.
FAU - Tian, Yunfei
AU  - Tian Y
AD  - Analytical & Testing Center, Sichuan University , Chengdu, Sichuan 610064, China.
FAU - Wu, Li
AU  - Wu L
AD  - Analytical & Testing Center, Sichuan University , Chengdu, Sichuan 610064, China.
FAU - Yang, Lu
AU  - Yang L
AD  - National Research Council Canada , Ottawa, Ontario K1A 0R6, Canada.
FAU - Hou, Xiandeng
AU  - Hou X
AD  - Key Laboratory of Green Chemistry & Technology of MOE, College of Chemistry, 
      Sichuan University , Chengdu, Sichuan 610064, China.
AD  - Analytical & Testing Center, Sichuan University , Chengdu, Sichuan 610064, China.
FAU - Zheng, Chengbin
AU  - Zheng C
AUID- ORCID: 0000-0002-7496-8335
AD  - Key Laboratory of Green Chemistry & Technology of MOE, College of Chemistry, 
      Sichuan University , Chengdu, Sichuan 610064, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20170124
PL  - United States
TA  - Anal Chem
JT  - Analytical chemistry
JID - 0370536
RN  - 0 (Mercury Compounds)
RN  - 0 (Nanotubes, Carbon)
SB  - IM
MH  - Animals
MH  - Carps/*metabolism
MH  - *Cold Temperature
MH  - Dietary Exposure
MH  - *Electrodes
MH  - Feasibility Studies
MH  - Limit of Detection
MH  - Mercury Compounds/*analysis/classification/pharmacokinetics
MH  - Microscopy, Electron, Scanning
MH  - Nanotubes, Carbon/chemistry
MH  - Reproducibility of Results
MH  - Spectrometry, Fluorescence/methods
MH  - Tissue Distribution
EDAT- 2017/02/18 06:00
MHDA- 2019/02/20 06:00
CRDT- 2017/02/18 06:00
PHST- 2017/02/18 06:00 [entrez]
PHST- 2017/02/18 06:00 [pubmed]
PHST- 2019/02/20 06:00 [medline]
AID - 10.1021/acs.analchem.6b04753 [doi]
PST - ppublish
SO  - Anal Chem. 2017 Feb 7;89(3):2093-2100. doi: 10.1021/acs.analchem.6b04753. Epub 
      2017 Jan 24.