PMID- 28210571
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2236-1960 (Print)
IS  - 2236-1960 (Electronic)
IS  - 2236-1960 (Linking)
VI  - 6
IP  - 4
DP  - 2016 Oct-Dec
TI  - Unmasking histoplasmosis immune reconstitution inflammatory syndrome in a patient 
      recently started on antiretroviral therapy.
PG  - 27-33
LID - 10.4322/acr.2016.048 [doi]
AB  - Histoplasmosis is the most common endemic mycoses among HIV-infected people. 
      Patients with suppressed cell immunity mainly due to HIV are at increased risk of 
      disseminated disease. Dermatological manifestations of immune reconstitution 
      inflammatory syndrome (IRIS) and cutaneous manifestations of histoplasmosis 
      similar to an IRIS event have been previously described. We report the case of a 
      43-year-old male who presented with cutaneous disseminated histoplasmosis due to 
      Histoplasma capsulatum var. capsulatum 4 months after the onset of the 
      antiretroviral therapy and some improvement in the immune reconstitution. After 2 
      weeks of amphotericin B and itraconazole therapy, the scheduled treatment 
      involved fluconazole maintenance therapy, which resulted in an improvement of his 
      skin lesions.
FAU - Kiggundu, Reuben
AU  - Kiggundu R
AD  - College of Health Sciences - Infectious Disease Institute - Makerere University, 
      Kampala - Uganda .
FAU - Nabeta, Henry W
AU  - Nabeta HW
AD  - College of Health Sciences - School of Medicine - Makerere University, Kampala - 
      Uganda .
FAU - Okia, Richard
AU  - Okia R
AD  - College of Health Sciences - School of Medicine - Makerere University, Kampala - 
      Uganda .
FAU - Rhein, Joshua
AU  - Rhein J
AD  - College of Health Sciences - Infectious Disease Institute - Makerere University, 
      Kampala - Uganda.; Department of Medicine - University of Minnesota, 
      Minneapolis/MN - USA.
FAU - Lukande, Robert
AU  - Lukande R
AD  - College of Health Sciences - School of Biomedical Sciences - Makerere University, 
      Kampala - Uganda .
LA  - eng
PT  - Case Reports
DEP - 20161230
PL  - Brazil
TA  - Autops Case Rep
JT  - Autopsy & case reports
JID - 101640070
EIN - Autops Case Rep. 2017 Mar 30;7(1):55. PMID: 28536689
PMC - PMC5304559
OTO - NOTNLM
OT  - Antiretroviral Therapy, Highly Active, Fluconazole
OT  - Histoplasmosis
OT  - Immune Reconstitution Inflammatory Syndrome
COIS- Conflict of interest: None
EDAT- 2017/02/18 06:00
MHDA- 2017/02/18 06:01
PMCR- 2016/12/30
CRDT- 2017/02/18 06:00
PHST- 2016/07/07 00:00 [received]
PHST- 2016/09/09 00:00 [accepted]
PHST- 2017/02/18 06:00 [entrez]
PHST- 2017/02/18 06:00 [pubmed]
PHST- 2017/02/18 06:01 [medline]
PHST- 2016/12/30 00:00 [pmc-release]
AID - autopsy-06-04027 [pii]
AID - 10.4322/acr.2016.048 [doi]
PST - epublish
SO  - Autops Case Rep. 2016 Dec 30;6(4):27-33. doi: 10.4322/acr.2016.048. eCollection 
      2016 Oct-Dec.