PMID- 28210705
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 5
IP  - 2
DP  - 2017 Feb
TI  - Gastric ESD may be useful as accurate staging and decision of future therapeutic 
      strategy.
PG  - E90-E95
LID - 10.1055/s-0042-119392 [doi]
AB  - Background and study aims We sometimes perform gastric endoscopic submucosal 
      dissection (ESD) for total pathologic diagnosis when preoperative diagnosis is 
      difficult. In the present study we analyzed the treatment outcomes and adverse 
      events of diagnostic ESD for early gastric cancer (EGC). Patients and methods We 
      conducted a retrospective analysis of 18 consecutive cases of EGC in 18 patients 
      with a suspected out-of-indication diagnosis who underwent diagnostic ESD, 
      between June 2010 and November 2014. The following parameters were examined: the 
      average length of the longer axis of the lesion; the procedure time; the rates of 
      en bloc resection (ER), complete en bloc resection (CER), and curative resection 
      (CR) as treatment outcomes; and the rates of perforation, delayed bleeding, 
      aspiration pneumonia, disease-related death, and emergency surgery as adverse 
      events. Results The treatment outcomes were as follows: average length of the 
      longer axis of the lesion, 27.4 +/- 10.0 mm; procedure time, 87.0 +/- 43.1 minutes; 
      ER rate, 18/18 (100.0 %); CER rate, 13/18 (72.2 %); CR rate, 4/18 (22.2 %). CR 
      rate was achieved 37.5 % for the lesions which preoperative diagnosis was more 
      than 30 mm (> 30 mm) in diameter differentiated type with mucosal 
      layer/submucosal layer 1 invasion and ulceration positive. The adverse events 
      (AEs) were perforation in 1 of 18 (5.5 %) patients and delayed bleeding in 1 of 
      18 (5.5 %). There were no other AEs. Conclusions Diagnostic ESD may be acceptable 
      for future therapeutic strategy when we unconfirmed the pre ESD diagnosis because 
      of lower rate of adverse events and high rate of ER.
FAU - Fujimoto, Ai
AU  - Fujimoto A
AD  - Center for Research and Development of Minimally Invasive Treatment, Cancer 
      Center, Keio University, Tokyo, Japan.
FAU - Goto, Osamu
AU  - Goto O
AD  - Center for Research and Development of Minimally Invasive Treatment, Cancer 
      Center, Keio University, Tokyo, Japan.
FAU - Nishizawa, Toshihiro
AU  - Nishizawa T
AD  - Center for Research and Development of Minimally Invasive Treatment, Cancer 
      Center, Keio University, Tokyo, Japan.
FAU - Ochiai, Yasutoshi
AU  - Ochiai Y
AD  - Center for Research and Development of Minimally Invasive Treatment, Cancer 
      Center, Keio University, Tokyo, Japan.
FAU - Horii, Joichiro
AU  - Horii J
AD  - Center for Research and Development of Minimally Invasive Treatment, Cancer 
      Center, Keio University, Tokyo, Japan.
FAU - Maehata, Tadateru
AU  - Maehata T
AD  - Center for Research and Development of Minimally Invasive Treatment, Cancer 
      Center, Keio University, Tokyo, Japan.
FAU - Akimoto, Teppei
AU  - Akimoto T
AD  - Center for Research and Development of Minimally Invasive Treatment, Cancer 
      Center, Keio University, Tokyo, Japan.
FAU - Kinoshita, Satoshi
AU  - Kinoshita S
AD  - Center for Research and Development of Minimally Invasive Treatment, Cancer 
      Center, Keio University, Tokyo, Japan.
FAU - Sagara, Seiji
AU  - Sagara S
AD  - Center for Research and Development of Minimally Invasive Treatment, Cancer 
      Center, Keio University, Tokyo, Japan.
FAU - Sasaki, Motoki
AU  - Sasaki M
AD  - Center for Research and Development of Minimally Invasive Treatment, Cancer 
      Center, Keio University, Tokyo, Japan.
FAU - Uraoka, Toshio
AU  - Uraoka T
AD  - Center for Research and Development of Minimally Invasive Treatment, Cancer 
      Center, Keio University, Tokyo, Japan.
FAU - Yahagi, Naohisa
AU  - Yahagi N
AD  - Center for Research and Development of Minimally Invasive Treatment, Cancer 
      Center, Keio University, Tokyo, Japan.
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC5303017
COIS- Competing interests None
EDAT- 2017/02/18 06:00
MHDA- 2017/02/18 06:01
PMCR- 2017/02/01
CRDT- 2017/02/18 06:00
PHST- 2017/02/18 06:00 [entrez]
PHST- 2017/02/18 06:00 [pubmed]
PHST- 2017/02/18 06:01 [medline]
PHST- 2017/02/01 00:00 [pmc-release]
AID - 10.1055/s-0042-119392 [doi]
PST - ppublish
SO  - Endosc Int Open. 2017 Feb;5(2):E90-E95. doi: 10.1055/s-0042-119392.