PMID- 28210707
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220318
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 5
IP  - 2
DP  - 2017 Feb
TI  - Assessing the safety of physician-directed nurse-administered propofol sedation 
      in low-risk patients undergoing endoscopy and colonoscopy.
PG  - E110-E115
LID - 10.1055/s-0042-121667 [doi]
AB  - Background and study aims Physician-directed nurse-administered balanced propofol 
      sedation (PhD NAPS) in patients undergoing endoscopy and/or colonoscopy is being 
      increasingly utilized worldwide. However, this method of sedation is not 
      universally employed in Australian hospitals due to concerns surrounding its 
      safety. The aim of this study was to assess the safety of PhD NAPS in low-risk 
      patients undergoing endoscopy and/or colonoscopy. Patients and methods This study 
      was conducted at a single tertiary teaching hospital in Adelaide, Australia. It 
      was a prospective study involving 1000 patients with an ASA score of 1 - 3 
      presenting with any indication for endoscopy, colonoscopy or both. A total of 981 
      patients (451 male) with a mean age of 53 years (range: 16 - 87) were recruited 
      from January 2010 to October 2012. 440 endoscopies, 420 colonoscopies, and 121 
      combined procedures were performed. The intra-procedural adverse events (AEs) 
      were recorded. Results There were no major intra-procedural adverse events. Minor 
      AEs occurred in 6.42 % of patients, and resolved spontaneously or with 
      intravenous fluid boluses in all cases. Conclusion PhD NAPS is safe when the 
      proceduralist and nursing staff are adequately trained and strict patient 
      selection criteria are used.
FAU - Sathananthan, Dharshan
AU  - Sathananthan D
AD  - Royal Adelaide Hospital - Gastroenerology, Adelaide, South Australia.
FAU - Young, Edward
AU  - Young E
AD  - University of Adelaide Medical School, Adelaide, South Australia.
FAU - Nind, Garry
AU  - Nind G
AD  - Lyell McEwin Hospital - Gastroenterology, Adelaide, South Australia.
FAU - George, Biju
AU  - George B
AD  - Lyell McEwin Hospital - Gastroenterology, Adelaide, South Australia.
FAU - Ashby, Angelie
AU  - Ashby A
AD  - University of Adelaide/Lyell McEwin Hospital, Endoscopy Unit, Elizabeth Vale, 
      South Australia.
FAU - Drummond, Sharon
AU  - Drummond S
AD  - University of Adelaide/Lyell McEwin Hospital, Endoscopy Unit, Elizabeth Vale, 
      South Australia.
FAU - Redel, Kasia
AU  - Redel K
AD  - University of Adelaide/Lyell McEwin Hospital, Endoscopy Unit, Elizabeth Vale, 
      South Australia.
FAU - Green, Neville
AU  - Green N
AD  - Lyell McEwin Hospital - Anaesthetics, Elizabeth Vale, South Australia.
FAU - Singh, Rajvinder
AU  - Singh R
AD  - Lyell McEwin Hospital - Gastroenterology, Adelaide, South Australia.
LA  - eng
PT  - Journal Article
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC5305421
COIS- Competing interests None
EDAT- 2017/02/18 06:00
MHDA- 2017/02/18 06:01
PMCR- 2017/02/01
CRDT- 2017/02/18 06:00
PHST- 2017/02/18 06:00 [entrez]
PHST- 2017/02/18 06:00 [pubmed]
PHST- 2017/02/18 06:01 [medline]
PHST- 2017/02/01 00:00 [pmc-release]
AID - 10.1055/s-0042-121667 [doi]
PST - ppublish
SO  - Endosc Int Open. 2017 Feb;5(2):E110-E115. doi: 10.1055/s-0042-121667.