PMID- 28220592 OWN - NLM STAT- MEDLINE DCOM- 20180924 LR - 20221207 IS - 1520-6777 (Electronic) IS - 0733-2467 (Linking) VI - 36 IP - 8 DP - 2017 Nov TI - Turkish validation of the urethral stricture surgery specific patient-reported outcome measure (USS-PROM) with supplemental assessment of erectile function and morbidity due to oral graft harvesting. PG - 2089-2095 LID - 10.1002/nau.23243 [doi] AB - AIMS: We validated a Turkish language version of the urethral stricture surgery specific patient-reported outcome measure (USS-PROM) in men undergoing anterior urethroplasty. We also investigated changes in erectile function (EF) and quality of life (QoL) due to oral mucosa graft (OMG) harvesting. METHODS: The USS-PROM captures lower urinary tract symptoms (LUTS), health related QoL (HRQoL) with EQ-5D visual analogue scale (EQ-VAS). To evaluate EF and OMG morbidity, we used International Index of Erectile Function (IIEF-5) and a self-completed questionnaire, respectively. Psychometric assessment of USS-PROM included test-retest reliability, internal consistency, criterion validity, and responsiveness. Objective evidence for urethroplasty success was demonstrated with fluoroscopic imaging and urethral calibration at post-operative six months. RESULTS: Among the 101 men included during study period, 42 had complete pre- and postoperative 6th month data for analysis. The test-retest intraclass correlation was 0.79. Cronbach's alpha for internal consistency of the LUTS construct was 0.79. There was a significant negative correlation between total LUTS scores and peak flow rates, both preoperatively (r = -0.478) and postoperatively (r = -0.508). Mean baseline EQ-VAS increased from 70 to 84 postoperatively (P < 0.001), indicating improved HRQoL. IIEF scores did not change significantly after urethroplasty. Early and late-term QoL impairment rates due to OMG harvesting were 28.9 and 13.1%, respectively. Three (7.1%) men required endoscopic intervention for recurrence within 6 months. CONCLUSIONS: Turkish version of USS-PROM showed comparable psychometric properties with the original version. Complementation of this instrument with additional measures that address sexual function and OMG morbidity provides better QoL assessment for urethral reconstruction. CI - (c) 2017 Wiley Periodicals, Inc. FAU - Onol, Fikret Fatih AU - Onol FF AD - Onol Urology, Istanbul, Turkey. FAU - Bindayi, Ahmet AU - Bindayi A AD - Department of Urology, Umraniye Training and Research Hospital, Istanbul, Turkey. FAU - Tahra, Ahmet AU - Tahra A AD - Department of Urology, Umraniye Training and Research Hospital, Istanbul, Turkey. FAU - Basibuyuk, Ismail AU - Basibuyuk I AD - Onol Urology, Istanbul, Turkey. FAU - Onol, Sinasi Yavuz AU - Onol SY AD - Onol Urology, Istanbul, Turkey. LA - eng PT - Journal Article PT - Validation Study DEP - 20170221 PL - United States TA - Neurourol Urodyn JT - Neurourology and urodynamics JID - 8303326 SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Erectile Dysfunction/*epidemiology MH - Humans MH - Lower Urinary Tract Symptoms/physiopathology MH - Male MH - Middle Aged MH - Mouth Diseases/*epidemiology MH - Mouth Mucosa/*transplantation MH - *Patient Reported Outcome Measures MH - Postoperative Complications/*epidemiology MH - Psychometrics MH - Quality of Life MH - Plastic Surgery Procedures MH - Reproducibility of Results MH - Surveys and Questionnaires MH - Urethra/physiopathology/*surgery MH - Urethral Stricture/physiopathology/*surgery MH - Young Adult OTO - NOTNLM OT - patient-reported outcomes measures OT - quality of life OT - urethroplasty EDAT- 2017/02/22 06:00 MHDA- 2018/09/25 06:00 CRDT- 2017/02/22 06:00 PHST- 2016/12/04 00:00 [received] PHST- 2017/01/12 00:00 [revised] PHST- 2017/01/18 00:00 [accepted] PHST- 2017/02/22 06:00 [pubmed] PHST- 2018/09/25 06:00 [medline] PHST- 2017/02/22 06:00 [entrez] AID - 10.1002/nau.23243 [doi] PST - ppublish SO - Neurourol Urodyn. 2017 Nov;36(8):2089-2095. doi: 10.1002/nau.23243. Epub 2017 Feb 21.