PMID- 28225030
OWN - NLM
STAT- MEDLINE
DCOM- 20181030
LR  - 20240324
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 7
DP  - 2017 Feb 22
TI  - Chemometric-assisted QuEChERS extraction method for post-harvest pesticide 
      determination in fruits and vegetables.
PG  - 42489
LID - 10.1038/srep42489 [doi]
LID - 42489
AB  - An effective analysis method was developed based on a chemometric tool for the 
      simultaneous quantification of five different post-harvest pesticides 
      (2,4-dichlorophenoxyacetic acid (2,4-D), carbendazim, thiabendazole, iprodione, 
      and prochloraz) in fruits and vegetables. In the modified QuEChERS (quick, easy, 
      cheap, effective, rugged and safe) method, the factors and responses for 
      optimization of the extraction and cleanup analyses were compared using the 
      Plackett-Burman (P-B) screening design. Furthermore, the significant factors 
      (toluene percentage, hydrochloric acid (HCl) percentage, and graphitized carbon 
      black (GCB) amount) were optimized using a central composite design (CCD) 
      combined with Derringer's desirability function (DF). The limits of 
      quantification (LOQs) were estimated to be 1.0 mug/kg for 2,4-D, carbendazim, 
      thiabendazole, and prochloraz, and 1.5 mug/kg for iprodione in food matrices. The 
      mean recoveries were in the range of 70.4-113.9% with relative standard 
      deviations (RSDs) of less than 16.9% at three spiking levels. The measurement 
      uncertainty of the analytical method was determined using the bottom-up approach, 
      which yielded an average value of 7.6%. Carbendazim was most frequently found in 
      real samples analyzed using the developed method. Consequently, the analytical 
      method can serve as an advantageous and rapid tool for determination of five 
      preservative pesticides in fruits and vegetables.
FAU - Li, Minmin
AU  - Li M
AD  - Institute of Food Science and Technology, Chinese Academy of Agricultural 
      Sciences/Key Laboratory of Agro-Products Processing/Laboratory of Agro-Products 
      Quality Safety Risk Assessment, Ministry of Agriculture, Beijing 100193, P.R. 
      China.
AD  - Functional and Evolutionary Entomology, Gembloux Agro-Bio-Tech, University of 
      Liege, Passage des Deportes 2, 5030 Gembloux, Belgium.
FAU - Dai, Chao
AU  - Dai C
AD  - Institute of Food Science and Technology, Chinese Academy of Agricultural 
      Sciences/Key Laboratory of Agro-Products Processing/Laboratory of Agro-Products 
      Quality Safety Risk Assessment, Ministry of Agriculture, Beijing 100193, P.R. 
      China.
FAU - Wang, Fengzhong
AU  - Wang F
AD  - Institute of Food Science and Technology, Chinese Academy of Agricultural 
      Sciences/Key Laboratory of Agro-Products Processing/Laboratory of Agro-Products 
      Quality Safety Risk Assessment, Ministry of Agriculture, Beijing 100193, P.R. 
      China.
FAU - Kong, Zhiqiang
AU  - Kong Z
AD  - Institute of Food Science and Technology, Chinese Academy of Agricultural 
      Sciences/Key Laboratory of Agro-Products Processing/Laboratory of Agro-Products 
      Quality Safety Risk Assessment, Ministry of Agriculture, Beijing 100193, P.R. 
      China.
AD  - Functional and Evolutionary Entomology, Gembloux Agro-Bio-Tech, University of 
      Liege, Passage des Deportes 2, 5030 Gembloux, Belgium.
FAU - He, Yan
AU  - He Y
AD  - Institute of Food Science and Technology, Chinese Academy of Agricultural 
      Sciences/Key Laboratory of Agro-Products Processing/Laboratory of Agro-Products 
      Quality Safety Risk Assessment, Ministry of Agriculture, Beijing 100193, P.R. 
      China.
FAU - Huang, Ya Tao
AU  - Huang YT
AD  - Institute of Food Science and Technology, Chinese Academy of Agricultural 
      Sciences/Key Laboratory of Agro-Products Processing/Laboratory of Agro-Products 
      Quality Safety Risk Assessment, Ministry of Agriculture, Beijing 100193, P.R. 
      China.
FAU - Fan, Bei
AU  - Fan B
AD  - Institute of Food Science and Technology, Chinese Academy of Agricultural 
      Sciences/Key Laboratory of Agro-Products Processing/Laboratory of Agro-Products 
      Quality Safety Risk Assessment, Ministry of Agriculture, Beijing 100193, P.R. 
      China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20170222
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
RN  - 0 (Pesticides)
RN  - 0 (Plant Extracts)
SB  - IM
MH  - Chromatography, High Pressure Liquid
MH  - Fruit/*chemistry
MH  - Pesticides/*chemistry/pharmacology
MH  - Plant Extracts/*chemistry/pharmacology
MH  - Tandem Mass Spectrometry
MH  - Vegetables/*chemistry
PMC - PMC5320482
COIS- The authors declare no competing financial interests.
EDAT- 2017/02/23 06:00
MHDA- 2018/10/31 06:00
PMCR- 2017/02/22
CRDT- 2017/02/23 06:00
PHST- 2016/08/17 00:00 [received]
PHST- 2017/01/11 00:00 [accepted]
PHST- 2017/02/23 06:00 [entrez]
PHST- 2017/02/23 06:00 [pubmed]
PHST- 2018/10/31 06:00 [medline]
PHST- 2017/02/22 00:00 [pmc-release]
AID - srep42489 [pii]
AID - 10.1038/srep42489 [doi]
PST - epublish
SO  - Sci Rep. 2017 Feb 22;7:42489. doi: 10.1038/srep42489.