PMID- 28235045
OWN - NLM
STAT- MEDLINE
DCOM- 20170815
LR  - 20220330
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 12
IP  - 2
DP  - 2017
TI  - Assessing upper-extremity motion: An innovative method to quantify functional 
      capacity in patients with chronic obstructive pulmonary disease.
PG  - e0172766
LID - 10.1371/journal.pone.0172766 [doi]
LID - e0172766
AB  - BACKGROUND: Assessment of functional capacity is important in directing chronic 
      obstructive pulmonary disease (COPD) care (e.g., rehabilitation and discharge 
      readiness), and in predicting outcomes (e.g., exacerbation, hospitalization, and 
      mortality). The 6-minute walk distance (6MWD) test for functional capacity 
      assessment, may be time-consuming and burdensome. OBJECTIVE: The purpose of the 
      current study was to evaluate an upper-extremity function (UEF) test for 
      assessing functional capacity in older adults with COPD. METHODS: In this 
      cross-sectional study, 49 older adults (>/=55 years) with diagnosed COPD were 
      recruited, and pulmonary function measures and 6MWD were obtained. Participants 
      wore wireless sensors on forearm and upper-arm and performed rapid elbow flexion 
      for 20 seconds (the UEF test). Slowness was assessed by measuring elbow speed, 
      and acceleration and weakness (muscle strength) were assessed by measuring power 
      of movement and elbow moment. RESULTS: Speed, power, and moment UEF parameters 
      were independently associated with 6MWD, when controlling for age, gender, and 
      body mass index (BMI) (r = 0.78, p < .001). Elbow moment showed significant 
      Pearson correlations with all pulmonary function measures and maximal 
      inspiratory/expiratory pressure measures (r = 0.35-0.69, p<0.02). CONCLUSIONS: 
      Results show promise of a quick upper-extremity measure of functional capacity in 
      patients with COPD, and as an outcome measure in clinical COPD trials.
FAU - Toosizadeh, Nima
AU  - Toosizadeh N
AD  - Arizona Center on Aging, University of Arizona, Department of Medicine, Tucson, 
      Arizona, United States of America.
AD  - Interdisciplinary Consortium on Advanced Motion Performance (iCAMP), Department 
      of Surgery, University of Arizona, Tucson, Arizona, United States of America.
FAU - Berry, Cristine
AU  - Berry C
AD  - Arizona Center on Aging, University of Arizona, Department of Medicine, Tucson, 
      Arizona, United States of America.
AD  - Pulmonary, Allergy, Critical Care, & Sleep Medicine, Department of Medicine, 
      University of Arizona, Tucson, Arizona, United States of America.
FAU - Bime, Christian
AU  - Bime C
AD  - Pulmonary, Allergy, Critical Care, & Sleep Medicine, Department of Medicine, 
      University of Arizona, Tucson, Arizona, United States of America.
FAU - Najafi, Bijan
AU  - Najafi B
AD  - Arizona Center on Aging, University of Arizona, Department of Medicine, Tucson, 
      Arizona, United States of America.
AD  - Interdisciplinary Consortium on Advanced Motion Performance (iCAMP), Department 
      of Surgery, University of Arizona, Tucson, Arizona, United States of America.
AD  - Division of Vascular Surgery and Endovascular Therapy, Michael E. DeBakey 
      Department of Surgery, Baylor College of Medicine, Houston, Texas, United States 
      of America.
FAU - Kraft, Monica
AU  - Kraft M
AD  - Pulmonary, Allergy, Critical Care, & Sleep Medicine, Department of Medicine, 
      University of Arizona, Tucson, Arizona, United States of America.
FAU - Mohler, Jane
AU  - Mohler J
AD  - Arizona Center on Aging, University of Arizona, Department of Medicine, Tucson, 
      Arizona, United States of America.
AD  - Interdisciplinary Consortium on Advanced Motion Performance (iCAMP), Department 
      of Surgery, University of Arizona, Tucson, Arizona, United States of America.
LA  - eng
PT  - Journal Article
DEP - 20170224
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Aged
MH  - Cross-Sectional Studies
MH  - Exercise Tolerance/physiology
MH  - Female
MH  - Humans
MH  - Lung/*physiopathology
MH  - Male
MH  - Middle Aged
MH  - Motion
MH  - Muscle Strength/physiology
MH  - Pulmonary Disease, Chronic Obstructive/diagnosis/*physiopathology
MH  - Upper Extremity/*physiopathology
MH  - Walk Test/*methods
PMC - PMC5325547
COIS- Competing Interests: The Upper-Extremity Frailty meter is protected by a patent 
      pending (US Patent 20,150,332,004). The patent is owned by the University of 
      Arizona, and N.T., J.M., and B.N. are listed as co-inventors on this patent 
      pending. No other conflict of interest is reported by other authors. This does 
      not alter our adherence to PLOS ONE policies on sharing data and materials.
EDAT- 2017/02/25 06:00
MHDA- 2017/08/16 06:00
PMCR- 2017/02/24
CRDT- 2017/02/25 06:00
PHST- 2016/10/13 00:00 [received]
PHST- 2017/02/09 00:00 [accepted]
PHST- 2017/02/25 06:00 [entrez]
PHST- 2017/02/25 06:00 [pubmed]
PHST- 2017/08/16 06:00 [medline]
PHST- 2017/02/24 00:00 [pmc-release]
AID - PONE-D-16-40941 [pii]
AID - 10.1371/journal.pone.0172766 [doi]
PST - epublish
SO  - PLoS One. 2017 Feb 24;12(2):e0172766. doi: 10.1371/journal.pone.0172766. 
      eCollection 2017.