PMID- 28239290 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200930 IS - 1428-2526 (Print) IS - 1897-4309 (Electronic) IS - 1428-2526 (Linking) VI - 20 IP - 6 DP - 2016 TI - Synchronous extraskeletal Ewing's sarcoma/PNET and gallbladder carcinoma: a case report and literature review. PG - 496-500 LID - 10.5114/wo.2016.65612 [doi] AB - Ewing's sarcoma (ES) and primitive neuroectodermal tumour (PNET) are now considered to be the same tumour and usually occur in long bones. Extraskeletal Ewing's sarcoma is an extremely rare neoplasm, accounting for 1% of soft tissue sarcomas, with most common location in the thorax. Gallbladder cancer (GBC) represents the most common type among the biliary tract cancers with a poor prognosis even among patients undergoing aggressive therapy. We present study of extraskeletal ES/PNET found in the hilus of the liver of an elderly, diagnosed one month prior with GBC woman. The patient underwent two cycles of chemotherapy SAIME/SAVAC for ES and thereafter was operated. During three-year follow-up no recurrence of ES/PNET has been reported. However, two years after chemotherapy the patient suffered a relapse of adenocarcinoma of the gallbladder and thus received palliative chemotherapy of gemcitabine and cisplatin. After 16 months of recurrence she died. To the best of our knowledge, this is the first case of ES/PNET located in the hilus of the liver and as a synchronous neoplasm. FAU - Plis, Andrzej AU - Plis A AD - Department of Clinical Oncology, Krakow University Hospital, Krakow, Poland; current employment: Clinic of Hematology and Oncology, Transplant and Palliative Medicine, University Hospital in Greifswald, Greifswald, Germany. FAU - Zygulska, Aneta AU - Zygulska A AD - Department of Clinical Oncology, Krakow University Hospital, Krakow, Poland. FAU - Puskulluoglu, Miroslawa AU - Puskulluoglu M AD - Department of Clinical Oncology, Krakow University Hospital, Krakow, Poland. FAU - Szczepanski, Wojciech AU - Szczepanski W AD - Department of Clinical and Experimental Pathomorphology, Jagiellonian University Medical College, Krakow, Poland. FAU - Bialas, Magdalena AU - Bialas M AD - Department of Clinical and Experimental Pathomorphology, Jagiellonian University Medical College, Krakow, Poland. FAU - Krupinski, Maciej AU - Krupinski M AD - John Paul II Specialist Hospital, Krakow, Poland. FAU - Krzemieniecki, Krzysztof AU - Krzemieniecki K AD - Department of Clinical Oncology, Krakow University Hospital, Krakow, Poland. LA - eng PT - Case Reports DEP - 20170112 PL - Poland TA - Contemp Oncol (Pozn) JT - Contemporary oncology (Poznan, Poland) JID - 101233223 PMC - PMC5320465 OTO - NOTNLM OT - PNET OT - extraskeletal Ewing's sarcoma OT - gallbladder carcinoma OT - hilus of liver EDAT- 2017/02/28 06:00 MHDA- 2017/02/28 06:01 PMCR- 2016/01/01 CRDT- 2017/02/28 06:00 PHST- 2014/06/05 00:00 [received] PHST- 2015/04/07 00:00 [accepted] PHST- 2017/02/28 06:00 [entrez] PHST- 2017/02/28 06:00 [pubmed] PHST- 2017/02/28 06:01 [medline] PHST- 2016/01/01 00:00 [pmc-release] AID - 29326 [pii] AID - 10.5114/wo.2016.65612 [doi] PST - ppublish SO - Contemp Oncol (Pozn). 2016;20(6):496-500. doi: 10.5114/wo.2016.65612. Epub 2017 Jan 12.