PMID- 28240952
OWN - NLM
STAT- MEDLINE
DCOM- 20170330
LR  - 20181202
IS  - 1943-5681 (Electronic)
IS  - 0002-9645 (Linking)
VI  - 78
IP  - 3
DP  - 2017 Mar
TI  - Reference intervals for serum reactive oxygen metabolites, biological antioxidant 
      potential, and oxidative stress index in adult rams.
PG  - 274-278
LID - 10.2460/ajvr.78.3.274 [doi]
AB  - OBJECTIVE To establish reference intervals for serum reactive oxygen metabolites 
      (ROMs), biological antioxidant potential (BAP), and oxidative stress index (OSi) 
      in adult rams by use of controlled preanalytic and analytic procedures. ANIMALS 
      123 healthy 1- to 4-year-old rams of 2 Greek breeds (Chios [n = 62] and Florina 
      [61]). PROCEDURES 4 hours after rams were fed, a blood sample was obtained from 
      each ram, and serum was harvested. Concentrations of ROMs and BAP were measured 
      colorimetrically on a spectrophotometric analyzer. The OSi was calculated as ROMs 
      concentration divided by BAP concentration. Combined and breed-specific reference 
      intervals were calculated by use of nonparametric and robust methods, 
      respectively. Reference intervals were defined as the 2.5th to 97.5th 
      percentiles. RESULTS Reference intervals for ROMs, BAP, and OSi for all rams 
      combined were 65 to 109 Carratelli units, 2,364 to 4,491 mumol/L, and 18.2 to 43.0 
      Carratelli units/(mmol/L), respectively. Reference intervals of Chios rams for 
      ROMs, BAP, and OSi were 56 to 113 Carratelli units, 2,234 to 4,290 mumol/L, and 
      12.9 to 38.4 Carratelli units/(mmol/L), respectively. Reference intervals of 
      Florina rams for ROMs, BAP, and OSi were 68 to 111 Carratelli units, 2,337 to 
      4,363 mumol/L, and 14.1 to 38.1 Carratelli units/(mmol/L), respectively. 
      CONCLUSIONS AND CLINICAL RELEVANCE Reference intervals calculated in this study 
      can be used as a guide for the interpretation of ROMs, BAP, and OSi results in 
      rams and, under appropriate conditions, can be adopted for use by veterinary 
      laboratories.
FAU - Oikonomidis, Ioannis L
AU  - Oikonomidis IL
FAU - Kiosis, Evangelos A
AU  - Kiosis EA
FAU - Brozos, Christos N
AU  - Brozos CN
FAU - Kritsepi-Konstantinou, Maria G
AU  - Kritsepi-Konstantinou MG
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Am J Vet Res
JT  - American journal of veterinary research
JID - 0375011
RN  - 0 (Antioxidants)
RN  - 0 (Reactive Oxygen Species)
RN  - S88TT14065 (Oxygen)
SB  - IM
MH  - Adult
MH  - Animals
MH  - Antioxidants/analysis
MH  - Humans
MH  - Male
MH  - *Oxidative Stress
MH  - Oxygen/*blood/metabolism
MH  - Reactive Oxygen Species/*blood/metabolism
MH  - Reference Values
MH  - Sheep/*blood
EDAT- 2017/02/28 06:00
MHDA- 2017/03/31 06:00
CRDT- 2017/02/28 06:00
PHST- 2017/02/28 06:00 [entrez]
PHST- 2017/02/28 06:00 [pubmed]
PHST- 2017/03/31 06:00 [medline]
AID - 10.2460/ajvr.78.3.274 [doi]
PST - ppublish
SO  - Am J Vet Res. 2017 Mar;78(3):274-278. doi: 10.2460/ajvr.78.3.274.