PMID- 28243123
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 1178-6930 (Print)
IS  - 1178-6930 (Electronic)
IS  - 1178-6930 (Linking)
VI  - 10
DP  - 2017
TI  - Prognostic value of the C-reactive protein/albumin ratio in patients with 
      laryngeal squamous cell carcinoma.
PG  - 879-884
LID - 10.2147/OTT.S128391 [doi]
AB  - PURPOSE: The present study was designed to retrospectively evaluate the 
      prognostic value of the C-reactive protein/albumin (CRP/ALB) ratio in laryngeal 
      squamous cell carcinoma (LSCC). METHODS: One hundred and twenty-nine newly 
      diagnosed LSCC patients admitted between May 2006 and October 2011 were 
      retrospectively reviewed. Their serum CRP and ALB were quantified preoperatively. 
      The relationship between the CRP/ALB ratio and the clinicopathologic features was 
      analyzed. Receiver operating characteristic curve was used to calculate the 
      prognostic value of the CRP/ALB ratio. Then, the Cox proportional hazards model 
      was used in univariate and multivariate analyses to identify significant 
      prognostic factors associated with disease-free survival and overall survival. 
      RESULTS: The cutoff value for CRP/ALB ratio was 0.047. An elevated CRP/ALB ratio 
      was significantly associated with nodal metastasis, late disease stage, and 
      recurrence. Also, high values of CRP/ALB ratio were significant predictors for 
      poor overall survival and disease-free survival on multivariate analysis. 
      CONCLUSION: Pretreatment CRP/ALB ratio may be a significant prognostic marker in 
      LSCC.
FAU - Yu, Shi-Tong
AU  - Yu ST
AD  - Department of Otolaryngology, Head and Neck Surgery; Guangdong Provincial Key 
      Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen 
      Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
FAU - Zhou, Zhiwei
AU  - Zhou Z
AD  - Department of Otolaryngology, Head and Neck Surgery; Guangdong Provincial Key 
      Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen 
      Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
FAU - Cai, Qian
AU  - Cai Q
AD  - Department of Otolaryngology, Head and Neck Surgery; Guangdong Provincial Key 
      Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen 
      Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
FAU - Liang, Faya
AU  - Liang F
AD  - Department of Otolaryngology, Head and Neck Surgery; Guangdong Provincial Key 
      Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen 
      Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
FAU - Han, Ping
AU  - Han P
AD  - Department of Otolaryngology, Head and Neck Surgery; Guangdong Provincial Key 
      Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen 
      Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
FAU - Chen, Renhui
AU  - Chen R
AD  - Department of Otolaryngology, Head and Neck Surgery; Guangdong Provincial Key 
      Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen 
      Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
FAU - Huang, Xiao-Ming
AU  - Huang XM
AD  - Department of Otolaryngology, Head and Neck Surgery; Guangdong Provincial Key 
      Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-sen 
      Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
LA  - eng
PT  - Journal Article
DEP - 20170215
PL  - New Zealand
TA  - Onco Targets Ther
JT  - OncoTargets and therapy
JID - 101514322
PMC - PMC5317306
OTO - NOTNLM
OT  - C-reactive protein/albumin ratio
OT  - laryngeal squamous cell carcinoma
OT  - prognosis
OT  - survival
COIS- Disclosure The authors report no conflicts of interest in this work.
EDAT- 2017/03/01 06:00
MHDA- 2017/03/01 06:01
PMCR- 2017/02/15
CRDT- 2017/03/01 06:00
PHST- 2017/03/01 06:00 [entrez]
PHST- 2017/03/01 06:00 [pubmed]
PHST- 2017/03/01 06:01 [medline]
PHST- 2017/02/15 00:00 [pmc-release]
AID - ott-10-879 [pii]
AID - 10.2147/OTT.S128391 [doi]
PST - epublish
SO  - Onco Targets Ther. 2017 Feb 15;10:879-884. doi: 10.2147/OTT.S128391. eCollection 
      2017.