PMID- 28246018
OWN - NLM
STAT- MEDLINE
DCOM- 20171127
LR  - 20180126
IS  - 1618-131X (Electronic)
IS  - 1438-4639 (Linking)
VI  - 220
IP  - 4
DP  - 2017 Jun
TI  - The impacts of emission trends of POPs on human concentration dynamics: Lessons 
      learned from a longitudinal study in Norway (1979-2007).
PG  - 776-781
LID - S1438-4639(16)30416-3 [pii]
LID - 10.1016/j.ijheh.2017.01.015 [doi]
AB  - BACKGROUND: In this short communication, our focus is on the relationship between 
      human concentrations of select persistent organic pollutants (POPs) and 
      environmental emissions. It is based on a longitudinal study (1979-2007) 
      conducted in Norway. OBJECTIVES: Our aim was to extract general insights from 
      observed and predicted temporal trends in human concentrations of 49 POPs to 
      assist in the design and interpretation of future monitoring studies. DISCUSSION: 
      Despite considerable decline for polychlorinated biphenyls (PCBs) and 
      organochlorine pesticides (OCPs) since 1986, the sum of the targeted POPs 
      increased from 1979 until 2001, with per- and polyfluorinated alkyl substances 
      (PFASs) dominating recent blood burden measurements. Specifically, the time 
      trends in serum concentrations of POPs, exemplified by PCB-153, 
      1,1'-(2,2,2-Trichloroethane-1,1-diyl)bis(4-chlorobenzene) (DDT) and 
      perfluorooctane sulfonic acid (PFOS), resembled the trends in available data on 
      their emissions, production or use. These observations suggest that 
      interpretations of human biomonitoring data on persistent compounds must consider 
      historic emissions, which likely vary spatially across the globe. Based on the 
      different temporal trends observed across POP groups, it is evident that 
      generalizations regarding temporal aspects have limitations. CONCLUSION: The 
      discussion herein underscores the importance of understanding temporal variations 
      in environmental emissions when designing and interpreting human biomonitoring 
      studies.
CI  - Copyright (c) 2017 Elsevier GmbH. All rights reserved.
FAU - Nost, Therese Haugdahl
AU  - Nost TH
AD  - NILU - Norwegian Institute for Air Research, The FRAM Centre, P.O. Box 6606 
      Langnes, NO-9296 Tromso, Norway; Department of Community Medicine, Faculty of 
      Health Sciences, UiT - The Arctic University of Norway, P.O. Box 6050 Langnes, 
      NO-9037 Tromso, Norway. Electronic address: therese.h.nost@uit.no.
FAU - Sandanger, Torkjel Manning
AU  - Sandanger TM
AD  - NILU - Norwegian Institute for Air Research, The FRAM Centre, P.O. Box 6606 
      Langnes, NO-9296 Tromso, Norway; Department of Community Medicine, Faculty of 
      Health Sciences, UiT - The Arctic University of Norway, P.O. Box 6050 Langnes, 
      NO-9037 Tromso, Norway.
FAU - Nieboer, Evert
AU  - Nieboer E
AD  - Department of Biochemistry and Biomedical Sciences, McMaster University,1280 Main 
      Street West, Hamilton, Ontario, Canada.
FAU - Odland, Jon Oyvind
AU  - Odland JO
AD  - Department of Community Medicine, Faculty of Health Sciences, UiT - The Arctic 
      University of Norway, P.O. Box 6050 Langnes, NO-9037 Tromso, Norway.
FAU - Breivik, Knut
AU  - Breivik K
AD  - NILU - Norwegian Institute for Air Research, P.O. Box 100, NO-2027 Kjeller, 
      Norway; Department of Chemistry, University of Oslo, P.O. Box 1033, NO-0315 Oslo, 
      Norway.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20170220
PL  - Germany
TA  - Int J Hyg Environ Health
JT  - International journal of hygiene and environmental health
JID - 100898843
RN  - 0 (Alkanesulfonic Acids)
RN  - 0 (Caprylates)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Fluorocarbons)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 947VD76D3L (perfluorooctanoic acid)
RN  - 9H2MAI21CL (perfluorooctane sulfonic acid)
SB  - IM
MH  - Adult
MH  - Aged
MH  - Alkanesulfonic Acids/blood
MH  - Caprylates/blood
MH  - Environmental Monitoring/*statistics & numerical data
MH  - Environmental Pollutants/*blood
MH  - Environmental Pollution/*statistics & numerical data
MH  - Fluorocarbons/blood
MH  - Humans
MH  - Hydrocarbons, Chlorinated/blood
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Norway
OTO - NOTNLM
OT  - Blood serum
OT  - Organochlorine pesticides
OT  - Per- and polyfluoroalkyl substances
OT  - Persistent organic pollutants
OT  - Polychlorinated biphenyls
OT  - Repeated measurements
EDAT- 2017/03/02 06:00
MHDA- 2017/11/29 06:00
CRDT- 2017/03/02 06:00
PHST- 2016/11/03 00:00 [received]
PHST- 2017/01/10 00:00 [revised]
PHST- 2017/01/12 00:00 [accepted]
PHST- 2017/03/02 06:00 [pubmed]
PHST- 2017/11/29 06:00 [medline]
PHST- 2017/03/02 06:00 [entrez]
AID - S1438-4639(16)30416-3 [pii]
AID - 10.1016/j.ijheh.2017.01.015 [doi]
PST - ppublish
SO  - Int J Hyg Environ Health. 2017 Jun;220(4):776-781. doi: 
      10.1016/j.ijheh.2017.01.015. Epub 2017 Feb 20.