PMID- 28248409 OWN - NLM STAT- MEDLINE DCOM- 20190501 LR - 20220408 IS - 1898-018X (Electronic) IS - 1898-018X (Linking) VI - 24 IP - 6 DP - 2017 TI - Immediate and long-term outcomes of percutaneous transcatheter pulmonary valve implantation. PG - 604-611 LID - 10.5603/CJ.a2017.0023 [doi] AB - BACKGROUND: Transcutaneous pulmonary valve replacement (TPVR) has become an alternative to heart surgery for patients after previous right ventricular outflow tract (RVOT) or pulmonary artery (PA) surgical interventions. The objective was to present immediate and long-term outcomes of trans notcutaneous pulmonary valve replacement. METHODS: Between 06/2009 and 06/2016, 46 patients underwent TPVR. Initial diagnoses included tetralogy of Fallot, common arterial trunk, transposition of great arteries post Rastelli correction, left ventricle outflow obstruction after Ross operation, pulmonary atresia, and isolated dysplastic pulmonary valve stenosis. Thirty eight (78%) patients had previously implanted conduits in the pulmonary position, the rest had either RVOT patch reconstruction (n = 6; 13%) or biological valve implantation (n = 2; 4%). They presented primarily with pulmonary stenosis (n = 18; 39%) or regurgitation (n = 28; 60%). RESULTS: All procedures were successful - 44 Melody and 2 Edwards-Sapien valves were implanted. Before each procedure exclusion of potential coronary compression and RVOT prestenting was performed. Significant RVOT systolic gradient reduction (from 35.3 +/- 19.5 to 13.5 +/- 7.1 mm Hg; p < 0.001) and decrease of right to left ventricle systolic pressure ratio from 0.58 +/- 0.18 to mean 0.37 +/- 0.1 (p < 0.001) was achieved. Also, in every patient PA-RVOT competence was restored, with minor in notcompetence in only a few patients. Post procedure follow-up ranged from 2 to 86 (mean 35.2) months. Follow-up fluoroscopy or chest X-ray revealed 6 stent fractures (2 stent defragmentation - with only 1 significant valve stenosis). CONCLUSIONS: Transcutaneous pulmonary valve replacement is a safe procedure with encouraging results, it also enables deferring surgical reintervention in the majority of patients. FAU - Fiszer, Roland AU - Fiszer R AD - Silesian Center for Heart Diseases Department of Congenital Heart Diseases and Pediatric Cardiology. rfiszer@gumed.edu.pl. FAU - Dryzek, Pawel AU - Dryzek P FAU - Szkutnik, Malgorzata AU - Szkutnik M FAU - Goreczny, Sebastian AU - Goreczny S FAU - Krawczuk, Alexandra AU - Krawczuk A FAU - Moll, Jadwiga AU - Moll J FAU - Moszura, Tomasz AU - Moszura T FAU - Pawlak, Szymon AU - Pawlak S FAU - Bialkowski, Jacek AU - Bialkowski J LA - eng PT - Journal Article PT - Multicenter Study DEP - 20170301 PL - Poland TA - Cardiol J JT - Cardiology journal JID - 101392712 SB - IM MH - Adolescent MH - Adult MH - Cardiac Catheterization/*methods MH - Child, Preschool MH - Female MH - Fluoroscopy MH - Follow-Up Studies MH - Heart Valve Prosthesis Implantation/*methods MH - Humans MH - Male MH - Prosthesis Design MH - Pulmonary Valve/diagnostic imaging/*surgery MH - Pulmonary Valve Insufficiency/diagnosis/*surgery MH - Pulmonary Valve Stenosis/diagnosis/*surgery MH - Retrospective Studies MH - Time Factors MH - Treatment Outcome OTO - NOTNLM OT - congenital heart disease OT - pulmonary valve OT - transcatheter valve implantation EDAT- 2017/03/02 06:00 MHDA- 2019/05/02 06:00 CRDT- 2017/03/02 06:00 PHST- 2016/09/27 00:00 [received] PHST- 2017/01/05 00:00 [accepted] PHST- 2017/12/28 00:00 [revised] PHST- 2017/03/02 06:00 [pubmed] PHST- 2019/05/02 06:00 [medline] PHST- 2017/03/02 06:00 [entrez] AID - VM/OJS/J/48959 [pii] AID - 10.5603/CJ.a2017.0023 [doi] PST - ppublish SO - Cardiol J. 2017;24(6):604-611. doi: 10.5603/CJ.a2017.0023. Epub 2017 Mar 1.