PMID- 28250621
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200930
IS  - 0974-777X (Print)
IS  - 0974-8245 (Electronic)
IS  - 0974-777X (Linking)
VI  - 9
IP  - 1
DP  - 2017 Jan-Mar
TI  - Evolving Rapid Methicillin-resistant Staphylococcus aureus Detection: Cover All 
      the Bases.
PG  - 18-22
LID - 10.4103/0974-777X.199997 [doi]
AB  - The dissemination of methicillin-resistant (MR) Staphylococcus aureus (SA) in 
      community and health-care settings is of great concern and associated with high 
      mortality and morbidity. Rapid detection of MRSA with short turnaround time can 
      minimize the time to initiate appropriate therapy and further promote infection 
      control. Early detection of MRSA directly from clinical samples is complicated by 
      the frequent association of MRSA with methicillin-susceptible SA (MSSA) and 
      coagulase-negative Staphylococcus (CoNS) species. Infection associated with true 
      MRSA or MSSA is differentiated from CoNS, requires target specific primers for 
      the presence of SA and mec A or nuc or fem A gene for confirmation of MR. 
      Recently, livestock-associated MRSA carrying mec C variant complicates the 
      epidemiology of MRSA further. Several commercial rapid molecular kits are 
      available with a different combination of these targets for the detection of MRSA 
      or MSSA. The claimed sensitivity and specificity of the currently available 
      commercial kits is varying, because of the different target combination used for 
      detection of SA and MR.
FAU - Bakthavatchalam, Yamuna Devi
AU  - Bakthavatchalam YD
AD  - Department of Clinical Microbiology, Christian Medical College, Vellore, Tamil 
      Nadu, India.
FAU - Nabarro, Laura E B
AU  - Nabarro LE
AD  - Department of Clinical Microbiology, Christian Medical College, Vellore, Tamil 
      Nadu, India; Department of Infectious Disease, Public Health England, London, UK.
FAU - Veeraraghavan, Balaji
AU  - Veeraraghavan B
AD  - Department of Clinical Microbiology, Christian Medical College, Vellore, Tamil 
      Nadu, India.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - India
TA  - J Glob Infect Dis
JT  - Journal of global infectious diseases
JID - 101521436
PMC - PMC5330039
OTO - NOTNLM
OT  - Livestock-methicillin-resistant Staphylococcus aureus
OT  - Xpert MRSA assay
OT  - methicillin-resistant Staphylococcus aureus
OT  - methicillin-susceptible Staphylococcus aureus
COIS- There are no conflicts of interest.
EDAT- 2017/03/03 06:00
MHDA- 2017/03/03 06:01
PMCR- 2017/01/01
CRDT- 2017/03/03 06:00
PHST- 2017/03/03 06:00 [entrez]
PHST- 2017/03/03 06:00 [pubmed]
PHST- 2017/03/03 06:01 [medline]
PHST- 2017/01/01 00:00 [pmc-release]
AID - JGID-9-18 [pii]
AID - 10.4103/0974-777X.199997 [doi]
PST - ppublish
SO  - J Glob Infect Dis. 2017 Jan-Mar;9(1):18-22. doi: 10.4103/0974-777X.199997.