PMID- 2825405
OWN - NLM
STAT- MEDLINE
DCOM- 19880121
LR  - 20190714
IS  - 0042-6822 (Print)
IS  - 0042-6822 (Linking)
VI  - 161
IP  - 2
DP  - 1987 Dec
TI  - Human T-cell leukemia virus type I isolates from Gabon and Ghana: comparative 
      analysis of proviral genomes.
PG  - 315-20
AB  - Two isolates of human T-cell leukemia virus type I (HTLV-I) were obtained from 
      lymphocyte cultures of a healthy carrier in Gabon and another in Ghana. Their 
      proviruses were analyzed by Southern blot hybridization and compared with 
      prototypical HTLV-I isolated in Japan and the United States. The provirus genomes 
      of both strains were highly homologous to the prototype HTLV-I along the whole 
      viral genome. The restriction endonuclease sites of the Ghanian isolate were 
      almost identical with those of the prototype HTLV-I, but 10 of 26 sites of the 
      Gabonese isolate were different from those of the prototype. Furthermore, the 
      restriction map of the Gabonese isolate resembled those of a simian T-cell 
      leukemia virus (STLV-I) isolated from a chimpanzee from Sierra Leone and a 
      variant of HTLV-I from Zaire (HTLV-Ib) more closely than those of any other known 
      HTLV-I. These results indicated the existence of some unique strains of HTLV-I 
      transmitted among African people, and the importance of clarifying the origin and 
      transmission of HTLV group viruses.
FAU - Fukasawa, M
AU  - Fukasawa M
AD  - Department of Animal Pathology, University of Tokyo, Tokyo.
FAU - Tsujimoto, H
AU  - Tsujimoto H
FAU - Ishikawa, K
AU  - Ishikawa K
FAU - Miura, T
AU  - Miura T
FAU - Ivanoff, B
AU  - Ivanoff B
FAU - Cooper, R W
AU  - Cooper RW
FAU - Frost, E
AU  - Frost E
FAU - Delaporte, E
AU  - Delaporte E
FAU - Mingle, J A
AU  - Mingle JA
FAU - Grant, F C
AU  - Grant FC
AU  - et al.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Virology
JT  - Virology
JID - 0110674
RN  - 0 (DNA, Viral)
RN  - EC 3.1.21.- (DNA Restriction Enzymes)
SB  - IM
MH  - Biological Evolution
MH  - DNA Restriction Enzymes
MH  - DNA, Viral/*genetics
MH  - Deltaretrovirus/*genetics/isolation & purification
MH  - Gabon
MH  - Ghana
MH  - Nucleic Acid Hybridization
EDAT- 1987/12/01 00:00
MHDA- 1987/12/01 00:01
CRDT- 1987/12/01 00:00
PHST- 1987/12/01 00:00 [pubmed]
PHST- 1987/12/01 00:01 [medline]
PHST- 1987/12/01 00:00 [entrez]
AID - 10.1016/0042-6822(87)90123-1 [doi]
PST - ppublish
SO  - Virology. 1987 Dec;161(2):315-20. doi: 10.1016/0042-6822(87)90123-1.