PMID- 28258448
OWN - NLM
STAT- MEDLINE
DCOM- 20180202
LR  - 20181202
IS  - 1432-2323 (Electronic)
IS  - 0364-2313 (Linking)
VI  - 41
IP  - 7
DP  - 2017 Jul
TI  - Surgical Treatment of Gastroesophageal Reflux Disease.
PG  - 1685-1690
LID - 10.1007/s00268-017-3955-1 [doi]
AB  - BACKGROUND: Gastroesophageal reflux disease (GERD) affects an estimated 20% of 
      the population in the USA, and its prevalence is increasing worldwide. Lifestyle 
      modifications and proton pump inhibitors (PPI) therapy are effective in the 
      majority of patients and remain the mainstay of treatment of GERD. However, some 
      patients will need surgical intervention because they have partial control of 
      symptoms, do not want to be on long-term medical treatment, or suffer 
      complications related to PPI therapy. AIMS: The aim of this study was to review 
      the available evidence that supports laparoscopic antireflux surgery, and to 
      study the effect of surgical therapy on the natural history of GERD. RESULTS: The 
      key elements for the success of antireflux surgery are proper patient selection, 
      careful analysis of the indications for surgery, complete pre-operative work-up, 
      and proper execution of the surgical technique. CONCLUSIONS: When the key 
      elements are respected, antireflux surgery is very effective in controlling GERD, 
      and it is associated to minimal morbidity and mortality.
FAU - Schlottmann, Francisco
AU  - Schlottmann F
AD  - Department of Surgery and Center for Esophageal Diseases and Swallowing, 
      University of North Carolina, 4030 Burnett-Womack Building, Campus Box 7081, 
      Chapel Hill, NC, 27599-7081, USA.
FAU - Herbella, Fernando A
AU  - Herbella FA
AD  - Department of Surgery, Escola Paulista de Medicina, Federal University of Sao 
      Paulo, Sao Paulo, Brazil.
FAU - Allaix, Marco E
AU  - Allaix ME
AD  - Department of Surgical Sciences, University of Torino, Turin, Italy.
FAU - Rebecchi, Fabrizio
AU  - Rebecchi F
AD  - Department of Surgical Sciences, University of Torino, Turin, Italy.
FAU - Patti, Marco G
AU  - Patti MG
AD  - Department of Surgery and Center for Esophageal Diseases and Swallowing, 
      University of North Carolina, 4030 Burnett-Womack Building, Campus Box 7081, 
      Chapel Hill, NC, 27599-7081, USA. Marco_patti@med.unc.edu.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - World J Surg
JT  - World journal of surgery
JID - 7704052
SB  - IM
MH  - Gastroesophageal Reflux/*surgery
MH  - Humans
MH  - Hydrogen-Ion Concentration
MH  - Laparoscopy
EDAT- 2017/03/05 06:00
MHDA- 2018/02/03 06:00
CRDT- 2017/03/05 06:00
PHST- 2017/03/05 06:00 [pubmed]
PHST- 2018/02/03 06:00 [medline]
PHST- 2017/03/05 06:00 [entrez]
AID - 10.1007/s00268-017-3955-1 [pii]
AID - 10.1007/s00268-017-3955-1 [doi]
PST - ppublish
SO  - World J Surg. 2017 Jul;41(7):1685-1690. doi: 10.1007/s00268-017-3955-1.