PMID- 28260264
OWN - NLM
STAT- MEDLINE
DCOM- 20180323
LR  - 20180323
IS  - 1600-0447 (Electronic)
IS  - 0001-690X (Linking)
VI  - 136
IP  - 1
DP  - 2017 Jul
TI  - Clinical high risk for psychosis: the association between momentary stress, 
      affective and psychotic symptoms.
PG  - 63-73
LID - 10.1111/acps.12714 [doi]
AB  - OBJECTIVE: The aim of this study was to assess associations between momentary 
      stress and both affective and psychotic symptoms in everyday life of individuals 
      at clinical high risk (CHR), compared to chronic psychotic patients and healthy 
      controls, in search for evidence of early stress sensitization. It also assessed 
      whether psychotic experiences were experienced as stressful. METHOD: The 
      experience sampling method was used to measure affective and psychotic reactivity 
      to everyday stressful activities, events and social situations in 22 CHR 
      patients, 24 patients with a psychotic disorder and 26 healthy controls. RESULTS: 
      Multilevel models showed significantly larger associations between negative 
      affect (NA) and activity-related stress for CHR patients than for psychotic 
      patients (P = 0.008) and for CHR compared to controls (P < 0.001). Similarly, the 
      association between activity-related stress and psychotic symptoms was larger in 
      CHR than in patients (P = 0.02). Finally, the association between NA and symptoms 
      (P < 0.001) was larger in CHR than in patients. CONCLUSION: Stress sensitization 
      seems to play a role particularly in the early phase of psychosis development as 
      results suggest that CHR patients are more sensitive to daily life stressors than 
      psychotic patients. In this early phase, psychotic experiences also contributed 
      to the experience of stress.
CI  - (c) 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - van der Steen, Y
AU  - van der Steen Y
AUID- ORCID: 0000-0001-9285-5513
AD  - Department of Psychiatry & Neuropsychology, School for Mental Health and 
      Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands.
AD  - Department of Neuroscience, Centre for Contextual Psychiatry, KU Leuven - 
      University of Leuven, Leuven, Belgium.
FAU - Gimpel-Drees, J
AU  - Gimpel-Drees J
AD  - Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
FAU - Lataster, T
AU  - Lataster T
AD  - Department of Psychiatry & Neuropsychology, School for Mental Health and 
      Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands.
FAU - Viechtbauer, W
AU  - Viechtbauer W
AD  - Department of Psychiatry & Neuropsychology, School for Mental Health and 
      Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands.
FAU - Simons, C J P
AU  - Simons CJP
AD  - Department of Psychiatry & Neuropsychology, School for Mental Health and 
      Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands.
AD  - GGzE, Institute for Mental Health Care Eindhoven en De Kempen, Eindhoven, The 
      Netherlands.
FAU - Lardinois, M
AU  - Lardinois M
AD  - Department of Psychiatry & Neuropsychology, School for Mental Health and 
      Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands.
FAU - Michel, T M
AU  - Michel TM
AD  - Department of Psychiatry Odense, Psychiatry in the region of Southern Denmark, 
      and Institute for Clincal Research, University of Southern Denmark, Denmark.
FAU - Janssen, B
AU  - Janssen B
AD  - Department of Psychiatry and Psychotherapy, Heinrich-Heine University Dusseldorf, 
      Dusseldorf, Germany.
FAU - Bechdolf, A
AU  - Bechdolf A
AD  - Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, 
      Germany.
FAU - Wagner, M
AU  - Wagner M
AD  - Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.
FAU - Myin-Germeys, I
AU  - Myin-Germeys I
AD  - Department of Psychiatry & Neuropsychology, School for Mental Health and 
      Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands.
AD  - Department of Neuroscience, Centre for Contextual Psychiatry, KU Leuven - 
      University of Leuven, Leuven, Belgium.
LA  - eng
PT  - Journal Article
DEP - 20170305
PL  - United States
TA  - Acta Psychiatr Scand
JT  - Acta psychiatrica Scandinavica
JID - 0370364
SB  - IM
MH  - Adult
MH  - Affect/*physiology
MH  - Ecological Momentary Assessment
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prodromal Symptoms
MH  - Psychotic Disorders/*physiopathology
MH  - Risk
MH  - Stress, Psychological/*physiopathology
MH  - Young Adult
OTO - NOTNLM
OT  - clinical high risk
OT  - daily life stressors
OT  - experience sampling method
OT  - psychotic disorder
EDAT- 2017/03/06 06:00
MHDA- 2018/03/24 06:00
CRDT- 2017/03/06 06:00
PHST- 2017/02/06 00:00 [accepted]
PHST- 2017/03/06 06:00 [pubmed]
PHST- 2018/03/24 06:00 [medline]
PHST- 2017/03/06 06:00 [entrez]
AID - 10.1111/acps.12714 [doi]
PST - ppublish
SO  - Acta Psychiatr Scand. 2017 Jul;136(1):63-73. doi: 10.1111/acps.12714. Epub 2017 
      Mar 5.