PMID- 28261355 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200930 IS - 1841-9038 (Print) IS - 2069-6116 (Electronic) IS - 1841-9038 (Linking) VI - 10 IP - 3 DP - 2015 Sep TI - Aldosterone Antagonists in ST Elevation Myocardial Infarction Patients with Low Left Ventricular Ejection Fraction: a Retrospective Study at Shahid Gangalal National Heart Centre, Bansbari, Kathmandu, Nepal. PG - 210-213 AB - BACKGROUND: Aldosterone antagonists (AA) improve survival in ST elevation myocardial infarction (STEMI) patients with left ventricular ejection fraction(LVEF) "T40% ,with either clinical heart failure or diabetes mellitus. Our aim was to assess the adherence of AA use in Shahid Gangalal National Heart Centre, Kathmandu, Nepal. METHODS: Medical records of 171 STEMI patients with LVEF "T40% and discharged from our centre between January 2012 and December 2012 were retrospectively reviewed, regarding the use of AA use. RESULTS: Among the 171 STEMI patients with LVEF "T40%, 5 patients were excluded study due to the presence of contraindication to AA therapy. Among the remaining 166 patients, only 135 (81.2%) patients were eligible for the AA therapy (58 patients with diabetes mellitus and clinical heart failure in 77 patients). Out of 58 diabetes mellitus patients, 28 (48.2%) patients were treated with AA. Whereas 39(50.6%) out of 77 patients with clinical heart failure were treated with AA. Overall, 67(49.6%) patients among 135 eligible patients were treated with AA. CONCLUSIONS: As in the international studies AA is under-used in our patient population. We still need some more effort to improve our prescription rate. FAU - Adhikari, Chandra Mani AU - Adhikari CM AD - Department of Cardiology, Shahid Gangalal National Heart Centre Bansbari, Kathmandu, Nepal. FAU - Rajbhandari, Sujeeb AU - Rajbhandari S AD - Department of Cardiology, Shahid Gangalal National Heart Centre Bansbari, Kathmandu, Nepal. FAU - Prajapati, Dipanker AU - Prajapati D AD - Department of Cardiology, Shahid Gangalal National Heart Centre Bansbari, Kathmandu, Nepal. FAU - Shrestha, Nagma AU - Shrestha N AD - Department of Cardiology, Shahid Gangalal National Heart Centre Bansbari, Kathmandu, Nepal. FAU - Baniya, Bibek AU - Baniya B AD - Department of Cardiology, Shahid Gangalal National Heart Centre Bansbari, Kathmandu, Nepal. FAU - Bogati, Amrit AU - Bogati A AD - Department of Cardiology, Shahid Gangalal National Heart Centre Bansbari, Kathmandu, Nepal. FAU - Gurung, Prakash AU - Gurung P AD - Department of Cardiology, Shahid Gangalal National Heart Centre Bansbari, Kathmandu, Nepal. FAU - Thapaliya, Suman AU - Thapaliya S AD - Department of Cardiology, Shahid Gangalal National Heart Centre Bansbari, Kathmandu, Nepal. LA - eng PT - Journal Article PL - Romania TA - Maedica (Bucur) JT - Maedica JID - 101526930 PMC - PMC5327828 EDAT- 2015/09/01 00:00 MHDA- 2015/09/01 00:01 PMCR- 2015/09/01 CRDT- 2017/03/07 06:00 PHST- 2017/03/07 06:00 [entrez] PHST- 2015/09/01 00:00 [pubmed] PHST- 2015/09/01 00:01 [medline] PHST- 2015/09/01 00:00 [pmc-release] PST - ppublish SO - Maedica (Bucur). 2015 Sep;10(3):210-213.