PMID- 28262909 OWN - NLM STAT- MEDLINE DCOM- 20170314 LR - 20240326 IS - 1680-0745 (Electronic) IS - 1995-1892 (Print) IS - 1015-9657 (Linking) VI - 28 IP - 1 DP - 2017 Jan/Feb TI - Peripartum cardiomyopathy among cardiovascular patients referred for echocardiography at Parirenyatwa Teaching Hospital, Harare, Zimbabwe. PG - 8-13 LID - 10.5830/CVJA-2016-043 [doi] AB - OBJECTIVES: The main aim was to evaluate the outcome of patients with peripartum cardiomyopathy (PPCM) within six months of diagnosis. The secondary aim was to describe demographic and clinical characteristics of patients with PPCM in Harare, Zimbabwe. METHODS: This was a prospective cohort study in which patients recruited into a detailed PPCM registry were followed up for six months. Echocardiograms were performed at enrolment, and three and six months after diagnosis, to determine left ventricular function. RESULTS: From 1 August 2012 to 31 July 2013, 43 patients with a new diagnosis of PPCM were recruited at Parirenyatwa Hospital in Harare. At six months, mean ejection fraction improved from 29.7 +/- 9.8 to 44.9 +/- 14.9%, p < 0.001 and New York Heart Association (NYHA) functional class improved significantly (p < 0.0001). Five (11.6%) patients died. CONCLUSIONS: Left ventricular function improved in a substantial number of patients (42.9%) in this Zimbabwean cohort compared to other African cohorts. However the mortality rate remained high. FAU - Gambahaya, Ellise Tapiwa AU - Gambahaya ET AD - College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe. Email: egambahaya@gmail.com. FAU - Hakim, James AU - Hakim J AD - College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe. FAU - Kao, David AU - Kao D AD - Division of Cardiology, Department of Medicine, University of Colorado Denver School of Medicine, Colorado, USA. FAU - Munyandu, Noleen AU - Munyandu N AD - College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe. FAU - Matenga, Jonathan AU - Matenga J AD - College of Health Sciences, University of Zimbabwe, Harare, Zimbabwe. LA - eng PT - Journal Article PL - South Africa TA - Cardiovasc J Afr JT - Cardiovascular journal of Africa JID - 101313864 SB - IM MH - Adult MH - Cardiomyopathy, Dilated/*diagnosis/epidemiology/physiopathology MH - Echocardiography MH - Female MH - Follow-Up Studies MH - Heart Ventricles/diagnostic imaging/*physiopathology MH - *Hospitals, Teaching MH - Humans MH - Incidence MH - *Peripartum Period MH - Pregnancy MH - *Pregnancy Complications, Cardiovascular MH - Prospective Studies MH - *Referral and Consultation MH - Ventricular Function, Left/*physiology MH - Zimbabwe/epidemiology PMC - PMC5423423 EDAT- 2017/03/07 06:00 MHDA- 2017/03/16 06:00 PMCR- 2017/01/01 CRDT- 2017/03/07 06:00 PHST- 2015/03/17 00:00 [received] PHST- 2016/04/03 00:00 [accepted] PHST- 2017/03/07 06:00 [entrez] PHST- 2017/03/07 06:00 [pubmed] PHST- 2017/03/16 06:00 [medline] PHST- 2017/01/01 00:00 [pmc-release] AID - 10.5830/CVJA-2016-043 [doi] PST - ppublish SO - Cardiovasc J Afr. 2017 Jan/Feb;28(1):8-13. doi: 10.5830/CVJA-2016-043.