PMID- 28262910 OWN - NLM STAT- MEDLINE DCOM- 20170314 LR - 20181113 IS - 1680-0745 (Electronic) IS - 1995-1892 (Print) IS - 1015-9657 (Linking) VI - 28 IP - 1 DP - 2017 Jan/Feb TI - Surgical placement of left ventricular lead for cardiac resynchronisation therapy after failure of percutaneous attempt. PG - 19-22 LID - 10.5830/CVJA-2016-046 [doi] AB - OBJECTIVE: Cardiac resynchronisation therapy has been shown to be an effective treatment to improve functional status and prolong survival of patients in advanced chronic heart failure. This study assessed the surgical outcomes of left anterior mini-thoracotomy for the implantation of left ventricular epicardial pacing leads in cardiac resynchronisation therapy. METHODS: Our study consisted of 30 consecutive patients who underwent cardiac resynchronisation therapy with a left thoracotomy between November 2010 and April 2012 in our clinic. Postoperative follow up included the assessment of New York Heart Association (NYHA) functional class, electrocardiography and echocardiography. RESULTS: There were 22 male and eight female patients with a mean age of 68 +/- 5.04 years. All patients were in NYHA class III or IV. Pre-procedure mean left ventricular ejection fraction was 28.1 +/- 4.5% and post-procedural ejection fraction improved to 31.7 +/- 5.1%. The pre-operative QRS duration changed from 171.7 +/- 10.8 to 156.2 +/- 4.4 ms after the operation. Also there was a significant reduction in left ventricular end-diastolic dimension from 6.98 +/- 0.8 to 6.72 +/- 0.8 mm (p < 0 .05), but no change in left ventricular end-systolic dimension and severity of mitral regurgitation. All patients had successful surgical left ventricular lead placement. There was no procedure-related mortality. The mean follow-up time was 40.4 months. CONCLUSION: Surgical epicardial left ventricular lead placement procedure is a safe and effective technique in patients with a failed percutaneous attempt. FAU - Ezelsoy, Mehmet AU - Ezelsoy M AD - Department of Cardiovascular Surgery, Bilim University, Istanbul, Turkey. Email: mehmet_ezelsoy@hotmail.com. FAU - Bayram, Muhammed AU - Bayram M AD - Department of Cardiovascular Surgery, Mehmet Akif Ersoy Hospital, Istanbul, Turkey. FAU - Yazici, Suleyman AU - Yazici S AD - Department of Cardiovascular Surgery, Bilim University, Istanbul, Turkey. FAU - Yazicioglu, Nuran AU - Yazicioglu N AD - Cardiology, Florence Nightingale Hospital, Istanbul, Turkey. FAU - Sagbas, Ertan AU - Sagbas E AD - Department of Cardiovascular Surgery, Bilim University, Istanbul, Turkey. LA - eng PT - Journal Article PL - South Africa TA - Cardiovasc J Afr JT - Cardiovascular journal of Africa JID - 101313864 SB - IM MH - Aged MH - Cardiac Resynchronization Therapy/*methods MH - Echocardiography MH - *Electrocardiography MH - Female MH - Follow-Up Studies MH - Heart Failure/diagnosis/physiopathology/*therapy MH - Heart Ventricles/diagnostic imaging/*physiopathology MH - Humans MH - Male MH - *Pacemaker, Artificial MH - Pericardium MH - Retrospective Studies MH - Ventricular Function, Left/*physiology PMC - PMC5423426 EDAT- 2017/03/07 06:00 MHDA- 2017/03/16 06:00 PMCR- 2017/01/01 CRDT- 2017/03/07 06:00 PHST- 2015/12/06 00:00 [received] PHST- 2016/04/03 00:00 [accepted] PHST- 2017/03/07 06:00 [entrez] PHST- 2017/03/07 06:00 [pubmed] PHST- 2017/03/16 06:00 [medline] PHST- 2017/01/01 00:00 [pmc-release] AID - 10.5830/CVJA-2016-046 [doi] PST - ppublish SO - Cardiovasc J Afr. 2017 Jan/Feb;28(1):19-22. doi: 10.5830/CVJA-2016-046.