PMID- 28268928
OWN - NLM
STAT- MEDLINE
DCOM- 20170630
LR  - 20200928
IS  - 2694-0604 (Electronic)
IS  - 2375-7477 (Linking)
VI  - 2016
DP  - 2016 Aug
TI  - Comparison between K-nearest-neighbor approaches for conditional entropy 
      estimation: Application to the assessment of the cardiac control in amyotrophic 
      lateral sclerosis patients.
PG  - 2933-2936
LID - 10.1109/EMBC.2016.7591344 [doi]
AB  - The study evaluates the k-nearest-neighbor (KNN) strategy for the assessment of 
      complexity of the cardiac neural control from spontaneous fluctuations of heart 
      period (HP). Two different procedures were assessed: i) the KNN estimation of the 
      conditional entropy (CE) proposed by Porta et al; ii) the KNN estimation of 
      mutual information proposed by Kozachenko-Leonenko, refined by 
      Kraskov-Stogbauer-Grassberger and here adapted for the CE estimation. The two 
      procedures were compared over HP variability recordings obtained at rest in 
      supine position and during head-up tilt (HUT) in amyotrophic lateral sclerosis 
      patients and healthy subjects. We found that the indexes derived from the two 
      procedures were significantly correlated and both methods were able to detect the 
      effect of HUT on HP complexity within the same group and distinguish the two 
      populations within the same experimental condition. We recommend the use of the 
      KNN strategy to quantify the dynamical complexity of cardiac neural control in 
      addition to more traditional approaches.
FAU - Porta, Alberto
AU  - Porta A
FAU - De Maria, Beatrice
AU  - De Maria B
FAU - Bari, Vlasta
AU  - Bari V
FAU - Marchi, Andrea
AU  - Marchi A
FAU - Marinou, Kalliopi
AU  - Marinou K
FAU - Sideri, Riccardo
AU  - Sideri R
FAU - Mora, Gabriele
AU  - Mora G
FAU - Dalla Vecchia, Laura
AU  - Dalla Vecchia L
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - United States
TA  - Annu Int Conf IEEE Eng Med Biol Soc
JT  - Annual International Conference of the IEEE Engineering in Medicine and Biology 
      Society. IEEE Engineering in Medicine and Biology Society. Annual International 
      Conference
JID - 101763872
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - *Algorithms
MH  - Amyotrophic Lateral Sclerosis/*physiopathology
MH  - Cluster Analysis
MH  - *Entropy
MH  - Female
MH  - Heart/*physiopathology
MH  - Heart Rate/physiology
MH  - Humans
MH  - Linear Models
MH  - Male
MH  - Middle Aged
MH  - Rest
MH  - Tilt-Table Test
EDAT- 2017/03/09 06:00
MHDA- 2017/07/01 06:00
CRDT- 2017/03/09 06:00
PHST- 2017/03/09 06:00 [entrez]
PHST- 2017/03/09 06:00 [pubmed]
PHST- 2017/07/01 06:00 [medline]
AID - 10.1109/EMBC.2016.7591344 [doi]
PST - ppublish
SO  - Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:2933-2936. doi: 
      10.1109/EMBC.2016.7591344.