PMID- 28273998
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240328
IS  - 2249-782X (Print)
IS  - 0973-709X (Electronic)
IS  - 0973-709X (Linking)
VI  - 11
IP  - 1
DP  - 2017 Jan
TI  - Effects of Laparoscopic Sleeve Gastrectomy on Central Obesity and Metabolic 
      Syndrome in Indian Adults- A Prospective Study.
PG  - PC01-PC04
LID - 10.7860/JCDR/2017/24477.9232 [doi]
AB  - INTRODUCTION: Increasing incidence of obesity in Indian population has led to an 
      exponential rise in the number of bariatric operations performed annually. 
      Laparoscopic Sleeve Gastrectomy (LSG) has been proposed to cause rapid remission 
      of Type 2 Diabetes Melitus (T2DM) and metabolic syndrome in a weight loss 
      independent manner. AIM: To evaluate the effects of LSG on metabolic syndrome and 
      central obesity in morbidly and severely obese Indian adults. Material and 
      Methods: Study was conducted on 91 morbidly obese [Body Mass Index (BMI)>40 
      kg/m(2)] and severely obese (BMI>35 kg/m(2)) individuals who were suffering from 
      diabetes, hypertension or dyslipidemia. The patients were followed up for six 
      months and the trends of glycaemic control, mean blood pressure, lipid profile, 
      weight loss parameters and changes in parameters of central obesity were studied. 
      RESULTS: Weight loss was significant at three months postsurgery and was 
      sustained through six months. There was significant improvement in glycaemic 
      control leading to reduction in need for oral hypoglycaemic agents or insulin in 
      majority of them and even discontinuation of these medications in few patients. 
      Hypertension and dyslipidemia also showed an improving trend through six months 
      postsurgery. There was a significant impact on reduction of central obesity in 
      these patients as marked by significant reduction in waist to hip ratio. 
      CONCLUSION: LSG produces sustainable weight loss with significant improvement in 
      glycaemic status and control of metabolic syndrome in severe to morbidly obese 
      patients. LSG is also efficacious in reducing central obesity in Indian 
      population which is a major depressive ailment amongst obese individuals.
FAU - Sethi, Pulkit
AU  - Sethi P
AD  - Senior resident, Department of G.I Surgery, Amrita institute of Medical Sciences 
      and Research , Kochi, Kerala, India .
FAU - Thillai, Manoj
AU  - Thillai M
AD  - Senior resident, Department of G.I Surgery, Amrita institute of Medical Sciences 
      and Research , Kochi, Kerala, India .
FAU - Nain, Prabhdeep Singh
AU  - Nain PS
AD  - Professor, Department of General surgery, Dayanand Medical College and Hospital , 
      Ludhiana, Punjab, India .
FAU - Ahuja, Ashish
AU  - Ahuja A
AD  - Associate professor, Department of General Surgery, Dayanand Medical College and 
      Hospital , Ludhiana, Punjab, India .
FAU - Vayoth, Sudheer Othiyil
AU  - Vayoth SO
AD  - Professor, Department of G.I Surgery, Amrita institute of Medical Sciences and 
      Research , Kochi, Kerala, India .
FAU - Khurana, Preetika
AU  - Khurana P
AD  - Assistant professor, Department of Anaesthesia, Amrita Institute of Medical 
      Sciences , Kochi, Kerala, India .
LA  - eng
PT  - Journal Article
DEP - 20170101
PL  - India
TA  - J Clin Diagn Res
JT  - Journal of clinical and diagnostic research : JCDR
JID - 101488993
PMC - PMC5324443
OTO - NOTNLM
OT  - Dyslipidemia
OT  - Glycosylated haemoglobin
OT  - Hypertension
OT  - Weight loss
EDAT- 2017/03/10 06:00
MHDA- 2017/03/10 06:01
PMCR- 2017/01/01
CRDT- 2017/03/10 06:00
PHST- 2016/09/28 00:00 [received]
PHST- 2016/12/08 00:00 [accepted]
PHST- 2017/03/10 06:00 [entrez]
PHST- 2017/03/10 06:00 [pubmed]
PHST- 2017/03/10 06:01 [medline]
PHST- 2017/01/01 00:00 [pmc-release]
AID - 10.7860/JCDR/2017/24477.9232 [doi]
PST - ppublish
SO  - J Clin Diagn Res. 2017 Jan;11(1):PC01-PC04. doi: 10.7860/JCDR/2017/24477.9232. 
      Epub 2017 Jan 1.