PMID- 28276781 OWN - NLM STAT- MEDLINE DCOM- 20180322 LR - 20221207 IS - 2000-1967 (Electronic) IS - 0300-9734 (Print) IS - 0300-9734 (Linking) VI - 122 IP - 2 DP - 2017 Jun TI - Association between numbers of decayed teeth and HbA1c in Japanese patients with type 2 diabetes mellitus. PG - 108-113 LID - 10.1080/03009734.2017.1285838 [doi] AB - BACKGROUND: Dental caries (DC) are more prevalent in individuals with diabetes than in healthy individuals. However, the association between glycaemic control and DC has not been well characterized in patients with type 2 diabetes mellitus (T2DM). We therefore assessed the association between glycated haemoglobin (HbA1c) serum concentrations and the prevalence of DC in patients with T2DM. METHODS: Retrospective analyses of data pertaining to 108 Japanese patients with T2DM hospitalized because of poor or worsened glycaemic control were included. We divided the patients based on HbA1c into two groups: HbA1c level >/=75 mmol/mol (9.0%) as poorly controlled T2DM, and HbA1c level <75 mmol/mol (9.0%) as a control group. We compared the association of lifestyle factors, dental caries, and periodontal health between patients with poorly controlled T2DM and controls. Stepwise multiple regression analyses were performed to evaluate the association between HbA1c, the absolute number of decayed teeth (DT), the sum of decayed, missing, and filled teeth, and the Met Need Index (MNI). RESULTS: DT was higher and MNI was lower in patients with poorly controlled T2DM as compared to that in controls (P = 0.006 and P = 0.004, respectively). Multiple regression analyses revealed a significant association between HbA1c levels and DT (adjusted beta = 0.039, 95% confidence interval [CI], 0.005 to 0.072, P = 0.025) and the MNI (adjusted beta = -0.216, 95% CI -0.374 to -0.058, P = 0.008). CONCLUSIONS: DT and MNI were associated with HbA1c in T2DM patients. FAU - Yonekura, Satoru AU - Yonekura S AD - a Department of Endocrinology , Tochigi Medical Center Shimotsuga, Ohira-machi Kawatsure 420-1 , Tochigi City , Tochigi , Japan. FAU - Usui, Masato AU - Usui M AD - b Usui Dental Office , 12-14 Numawada-machi , Tochigi City , Tochigi , Japan. FAU - Murano, Shunichi AU - Murano S AD - a Department of Endocrinology , Tochigi Medical Center Shimotsuga, Ohira-machi Kawatsure 420-1 , Tochigi City , Tochigi , Japan. LA - eng PT - Journal Article DEP - 20170303 PL - Sweden TA - Ups J Med Sci JT - Upsala journal of medical sciences JID - 0332203 RN - 0 (Blood Glucose) RN - 0 (Glycated Hemoglobin A) SB - IM MH - Adult MH - Aged MH - Aged, 80 and over MH - Blood Glucose/analysis MH - Body Mass Index MH - Dental Caries/*blood/complications MH - Diabetes Complications/*blood MH - Diabetes Mellitus, Type 2/*blood/complications MH - Female MH - Glycated Hemoglobin/*analysis MH - Hospitalization MH - Humans MH - Japan MH - Life Style MH - Male MH - Middle Aged MH - Regression Analysis MH - Retrospective Studies PMC - PMC5441370 OTO - NOTNLM OT - Dental caries OT - diabetes OT - haemoglobin A1c OT - systemic disease EDAT- 2017/03/10 06:00 MHDA- 2018/03/23 06:00 PMCR- 2017/06/01 CRDT- 2017/03/10 06:00 PHST- 2017/03/10 06:00 [pubmed] PHST- 2018/03/23 06:00 [medline] PHST- 2017/03/10 06:00 [entrez] PHST- 2017/06/01 00:00 [pmc-release] AID - iups-122-108 [pii] AID - 10.1080/03009734.2017.1285838 [doi] PST - ppublish SO - Ups J Med Sci. 2017 Jun;122(2):108-113. doi: 10.1080/03009734.2017.1285838. Epub 2017 Mar 3.