PMID- 28277878 OWN - NLM STAT- MEDLINE DCOM- 20180604 LR - 20180604 IS - 1556-9535 (Electronic) IS - 1556-9527 (Linking) VI - 36 IP - 4 DP - 2017 Dec TI - Effect of smoking on the thickness of retinal layers in healthy smokers. PG - 366-369 LID - 10.1080/15569527.2017.1300162 [doi] AB - PURPOSE: To compare the thicknesses of the retinal layers in smokers with those of nonsmoking healthy subjects using spectral-domain optical coherence tomography (SD-OCT). METHODS: One hundred and eight subjects were included in the study. Two groups were separated as smokers and nonsmokers. Both groups were chosen to be similar in terms of age and gender. SD-OCT images were generated with Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany). An automated algorithm was developed to segment the macular retina into eight layers and quantitate the thickness of each layer for the fovea, parafovea and perifovea. RESULTS: The mean smoking history was 18.33 +/- 8.45 years (range: 10-40). The mean number of pack-years was 22.22 +/- 15.51 (range: 10-80). No significant difference was observed regarding retinal layer measurements between the smoker and nonsmoker groups. Also, no significant difference was observed for central macular thicknesses at 1000, 3000, and 6000 mum between two groups. CONCLUSION: The thickness of retinal layers in healthy smokers was similar to those of healthy individuals. FAU - Duman, Rahmi AU - Duman R AD - a Department of Ophthalmology, School of Medicine , Afyon Kocatepe University , Afyonkarahisar , Turkey. FAU - Duman, Resat AU - Duman R AD - a Department of Ophthalmology, School of Medicine , Afyon Kocatepe University , Afyonkarahisar , Turkey. FAU - Sabaner, Mehmet Cem AU - Sabaner MC AD - a Department of Ophthalmology, School of Medicine , Afyon Kocatepe University , Afyonkarahisar , Turkey. FAU - Cetinkaya, Ersan AU - Cetinkaya E AD - a Department of Ophthalmology, School of Medicine , Afyon Kocatepe University , Afyonkarahisar , Turkey. LA - eng PT - Journal Article DEP - 20170321 PL - England TA - Cutan Ocul Toxicol JT - Cutaneous and ocular toxicology JID - 101266892 SB - IM MH - Adult MH - Female MH - Humans MH - Male MH - Middle Aged MH - Retina/*anatomy & histology/diagnostic imaging MH - Smokers MH - *Smoking MH - Tomography, Optical Coherence OTO - NOTNLM OT - Retinal layer OT - smoking OT - spectral-domain OCT EDAT- 2017/03/10 06:00 MHDA- 2018/06/05 06:00 CRDT- 2017/03/10 06:00 PHST- 2017/03/10 06:00 [pubmed] PHST- 2018/06/05 06:00 [medline] PHST- 2017/03/10 06:00 [entrez] AID - 10.1080/15569527.2017.1300162 [doi] PST - ppublish SO - Cutan Ocul Toxicol. 2017 Dec;36(4):366-369. doi: 10.1080/15569527.2017.1300162. Epub 2017 Mar 21.