PMID- 28280372 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20200929 IS - 1178-6965 (Print) IS - 1178-6965 (Electronic) IS - 1178-6965 (Linking) VI - 10 DP - 2017 TI - Pediatric anaphylaxis and hyper IgE syndrome. PG - 31-33 LID - 10.2147/JAA.S129160 [doi] AB - Patients with autosomal-dominant (AD) hyper immunoglobulin E (IgE) syndrome (HIES) or Job syndrome develop frequent dermatologic and pulmonary infections. As patients have an extreme elevation of IgE levels, this database analysis study sought to study the association between AD HIES, Job syndrome, and anaphylaxis. HIES is a heterogeneous group of immune disorders characterized by extremely elevated levels of serum IgE. Although the molecular defects and clinical phenotypes found in association with Job syndrome are well characterized, the association with severe allergic reactions and anaphylaxis is a subject of ongoing investigation. FAU - Dosanjh, Amrita AU - Dosanjh A AD - Department of Pediatrics, Rady Childrens Hospital, San Diego, CA, USA. LA - eng PT - Journal Article DEP - 20170228 PL - New Zealand TA - J Asthma Allergy JT - Journal of asthma and allergy JID - 101543450 PMC - PMC5338956 OTO - NOTNLM OT - allergy OT - anaphylaxis OT - hyper IgE syndrome OT - pediatrics COIS- Disclosure The author reports no conflicts of interest in this work. EDAT- 2017/03/11 06:00 MHDA- 2017/03/11 06:01 PMCR- 2017/02/28 CRDT- 2017/03/11 06:00 PHST- 2017/03/11 06:00 [entrez] PHST- 2017/03/11 06:00 [pubmed] PHST- 2017/03/11 06:01 [medline] PHST- 2017/02/28 00:00 [pmc-release] AID - jaa-10-031 [pii] AID - 10.2147/JAA.S129160 [doi] PST - epublish SO - J Asthma Allergy. 2017 Feb 28;10:31-33. doi: 10.2147/JAA.S129160. eCollection 2017.