PMID- 28280631
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200929
IS  - 2078-6891 (Print)
IS  - 2219-679X (Electronic)
IS  - 2078-6891 (Linking)
VI  - 8
IP  - 1
DP  - 2017 Feb
TI  - Gastric metastasis of bilateral breast cancer.
PG  - E16-E20
LID - 10.21037/jgo.2016.10.03 [doi]
AB  - Breast cancer is the most common malignancy in women. The most frequent 
      metastatic sites are lung, bone, liver and brain. On the other hand, gastric 
      metastases are rare. Synchronous bilateral breast cancer (SBBC) occurs rarely. 
      Lobular carcinoma is the histological type most often associated with bilateral 
      breast carcinomas and gastric metastases. We made a retrospective study including 
      four patients followed in the Salah Azaiez Institute, for a bilateral breast 
      cancer with gastric metastases. We analyzed the epidemiological, anatomoclinical 
      and therapeutic particularities of this rare entity. Symptoms were unspecific. 
      The diagnosis of gastric metastasis of the SBBC was confirmed by a 
      histopathological examination of an endoscopic biopsy. The median age was 46.2 
      years (range, 36-51 years) and the median time until the gastric involvement was 
      19 months (range, 0-41 months). None of patients had a surgical treatment for the 
      gastric location. All Patients received at least one line of chemotherapy and 
      radiotherapy. Median survival following the detection of gastric involvement was 
      22 months (range, 1-56 months). Gastric metastases from breast cancer are rare 
      and frequently associated with other distant metastasis. Symptoms are unspecific 
      and endoscopy may not be contributive. Therefore, gastric involvement is 
      underestimated. Lobular infiltrating carcinoma (LIC) is the most histological 
      type incriminated in its occurrence. The supply of immunohistochemistry is 
      crucial to distinguish between primary or metastatic gastric cancer.
FAU - Jmour, Omar
AU  - Jmour O
AD  - Department of Radiation Oncology, Salah Azaiez Institute, Faculty of Medicine of 
      Tunis, Tunis El Manar University, Tunis, Tunisia.
FAU - Belaid, Asma
AU  - Belaid A
AD  - Department of Radiation Oncology, Salah Azaiez Institute, Faculty of Medicine of 
      Tunis, Tunis El Manar University, Tunis, Tunisia.
FAU - Mghirbi, Fahmi
AU  - Mghirbi F
AD  - Department of Medical Oncology, Salah Azaiez Institute, Faculty of Medicine of 
      Tunis, Tunis El Manar University, Tunis, Tunisia.
FAU - Behi, Khalil
AU  - Behi K
AD  - Department of Medical Oncology, Salah Azaiez Institute, Faculty of Medicine of 
      Tunis, Tunis El Manar University, Tunis, Tunisia.
FAU - Doghri, Raoudha
AU  - Doghri R
AD  - Department of Pathology, Salah Azaiez Institute, Faculty of Medicine of Tunis, 
      Tunis El Manar University, Tunis, Tunisia.
FAU - Benna, Farouk
AU  - Benna F
AD  - Department of Radiation Oncology, Salah Azaiez Institute, Faculty of Medicine of 
      Tunis, Tunis El Manar University, Tunis, Tunisia.
LA  - eng
PT  - Case Reports
PL  - China
TA  - J Gastrointest Oncol
JT  - Journal of gastrointestinal oncology
JID - 101557751
PMC - PMC5334049
OTO - NOTNLM
OT  - Breast cancer
OT  - gastric metastasis
OT  - therapy
COIS- Conflicts of Interest: The authors have no conflicts of interest to declare.
EDAT- 2017/03/11 06:00
MHDA- 2017/03/11 06:01
PMCR- 2017/02/01
CRDT- 2017/03/11 06:00
PHST- 2017/03/11 06:00 [entrez]
PHST- 2017/03/11 06:00 [pubmed]
PHST- 2017/03/11 06:01 [medline]
PHST- 2017/02/01 00:00 [pmc-release]
AID - jgo-08-01-E16 [pii]
AID - 10.21037/jgo.2016.10.03 [doi]
PST - ppublish
SO  - J Gastrointest Oncol. 2017 Feb;8(1):E16-E20. doi: 10.21037/jgo.2016.10.03.