PMID- 28280745 OWN - NLM STAT- MEDLINE DCOM- 20170615 LR - 20221207 IS - 2314-6753 (Electronic) IS - 2314-6745 (Print) VI - 2017 DP - 2017 TI - Medication Adherence Mediates the Association between Type D Personality and High HbA1c Level in Chinese Patients with Type 2 Diabetes Mellitus: A Six-Month Follow-Up Study. PG - 7589184 LID - 10.1155/2017/7589184 [doi] LID - 7589184 AB - Aims. To examine the association between Type D personality and HbA1c level and to explore the mediating role of medication adherence between them in patients with type 2 diabetes mellitus (T2DM). Methods. 330 patients went on to complete a self-report measure of medication adherence and the HbA1c tests. Chi-square test, T test, Ordinary Least Square Regression (OLS), and Recentered Influence Function Regression (RIF) were employed. Results. Patients with Type D personality had significantly higher HbA1c value (P < 0.01). When Type D personality was operationalized as a categorical variable, SI was associated with HbA1c (P < 0.01). When NA, SI, and their interaction term were entered into regression, all of them were no longer associated with HbA1c level (P > 0.1). On the other hand, when Type D personality was operationalized as a continuous variable, only SI trait was associated with HbA1c level (P < 0.01). When NA, SI, and NA x SI term together were entered into regression, only SI was not related to HbA1c level. Furthermore, medication adherence had a significant mediation effect between Type D personality and HbA1c, accounting for 54.43% of the total effect. Conclusion. Type D personality was associated with HbA1c in direct and indirect ways, and medication adherence acted as a mediator role. FAU - Li, Xuemei AU - Li X AD - School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China; Clinics of Cadre, Department of Outpatient, General Hospital of the People's Liberation Army (301 Hospital), Beijing 100853, China. FAU - Gao, Min AU - Gao M AD - School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China. FAU - Zhang, Shengfa AU - Zhang S AD - School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China. FAU - Xu, Huiwen AU - Xu H AD - Department of Public Health Sciences, University of Rochester School of Medicine & Dentistry, Rochester, NY 14642, USA. FAU - Zhou, Huixuan AU - Zhou H AD - School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China. FAU - Wang, Xiaohua AU - Wang X AD - School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China. FAU - Qu, Zhiyong AU - Qu Z AD - School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China. FAU - Guo, Jing AU - Guo J AD - Department of Sociology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China. FAU - Zhang, Weijun AU - Zhang W AUID- ORCID: 0000-0003-3436-3371 AD - School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China. FAU - Tian, Donghua AU - Tian D AUID- ORCID: 0000-0003-4586-5502 AD - School of Social Development and Public Policy, China Institute of Health, Beijing Normal University, Beijing 100875, China. LA - eng PT - Journal Article DEP - 20170209 PL - England TA - J Diabetes Res JT - Journal of diabetes research JID - 101605237 RN - 0 (Glycated Hemoglobin A) RN - 0 (hemoglobin A1c protein, human) SB - IM MH - China MH - Diabetes Mellitus, Type 2/blood/*drug therapy/psychology MH - Female MH - Follow-Up Studies MH - Glycated Hemoglobin/*analysis MH - Humans MH - Male MH - Medication Adherence/*psychology MH - Middle Aged MH - *Type D Personality PMC - PMC5322451 COIS- The authors declare that they have no competing interests. EDAT- 2017/03/11 06:00 MHDA- 2017/11/18 06:00 PMCR- 2017/02/09 CRDT- 2017/03/11 06:00 PHST- 2016/09/16 00:00 [received] PHST- 2016/11/23 00:00 [revised] PHST- 2016/12/07 00:00 [accepted] PHST- 2017/03/11 06:00 [entrez] PHST- 2017/03/11 06:00 [pubmed] PHST- 2017/11/18 06:00 [medline] PHST- 2017/02/09 00:00 [pmc-release] AID - 10.1155/2017/7589184 [doi] PST - ppublish SO - J Diabetes Res. 2017;2017:7589184. doi: 10.1155/2017/7589184. Epub 2017 Feb 9.