PMID- 28285028
OWN - NLM
STAT- MEDLINE
DCOM- 20180730
LR  - 20180829
IS  - 1573-2509 (Electronic)
IS  - 0920-9964 (Linking)
VI  - 190
DP  - 2017 Dec
TI  - Social cognition of patients with schizophrenia across the phases of illness - A 
      longitudinal study.
PG  - 150-159
LID - S0920-9964(17)30123-8 [pii]
LID - 10.1016/j.schres.2017.03.008 [doi]
AB  - AIM: This longitudinal study aimed to evaluate social cognition of patients with 
      schizophrenia at two points, i.e., during the symptomatic phase and clinical 
      remission phase. Additional aim was to evaluate the relationship of social 
      cognition with psychopathology and functional outcome. METHODOLOGY: Fifty-one 
      patients (N=51) were evaluated on Social Cognition Rating Tools in Indian Setting 
      (SOCRATIS), Positive and Negative Syndrome Scale (PANSS), Global Assessment of 
      Functioning (GAF), Socio-occupational functioning scale (SOFS) and Indian 
      Disability Evaluation and Assessment Scale (IDEAS) during the symptomatic phase 
      of illness. These patients were followed-up longitudinally for achieving clinical 
      remission. Out of the 51 patients, 32 patients underwent second assessment after 
      a mean duration of 143 (SD 34.9) days, while in clinical remission. Data of 111 
      healthy controls was used for comparison. RESULTS: Social cognitive deficits were 
      present in both the phases of illness. However, when the baseline and follow-up 
      data was compared, it was evident that the severity of social cognition deficits 
      is lower during the clinical remission phase. Higher levels of social cognitive 
      deficits in both phases of illness are associated with higher socio-occupational 
      dysfunction and higher disability. CONCLUSION: Present study suggests that 
      impairment in social cognition in patients with schizophrenia is present both in 
      symptomatic and remission phase, with higher level of deficits during the 
      symptomatic phase. Social cognition impairments are associated with poor social 
      and occupational functioning and higher level of disability.
CI  - Copyright (c) 2017 Elsevier B.V. All rights reserved.
FAU - Valaparla, Vijaya Lakshmi
AU  - Valaparla VL
AD  - Department of Psychiatry, Kasturba Medical College, Manipal, India.
FAU - Nehra, Ritu
AU  - Nehra R
AD  - Department of Psychiatry, PGIMER, Chandigarh, India.
FAU - Mehta, Urvakhsh Meherwan
AU  - Mehta UM
AD  - Department of Psychiatry, NIMHANS, Bangalore, India.
FAU - Thirthalli, Jagadisha
AU  - Thirthalli J
AD  - Department of Psychiatry, NIMHANS, Bangalore, India.
FAU - Grover, Sandeep
AU  - Grover S
AD  - Department of Psychiatry, PGIMER, Chandigarh, India. Electronic address: 
      drsandeepg2002@yahoo.com.
LA  - eng
PT  - Journal Article
DEP - 20170309
PL  - Netherlands
TA  - Schizophr Res
JT  - Schizophrenia research
JID - 8804207
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - *Cognition
MH  - Disability Evaluation
MH  - Disease Progression
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - Psychiatric Status Rating Scales
MH  - Remission Induction
MH  - Schizophrenia/*therapy
MH  - *Schizophrenic Psychology
MH  - Severity of Illness Index
MH  - *Social Perception
MH  - Socioeconomic Factors
MH  - Young Adult
OTO - NOTNLM
OT  - Disability
OT  - Functioning
OT  - Schizophrenia
OT  - Social cognition
EDAT- 2017/03/13 06:00
MHDA- 2018/07/31 06:00
CRDT- 2017/03/13 06:00
PHST- 2016/09/24 00:00 [received]
PHST- 2017/02/26 00:00 [revised]
PHST- 2017/03/02 00:00 [accepted]
PHST- 2017/03/13 06:00 [pubmed]
PHST- 2018/07/31 06:00 [medline]
PHST- 2017/03/13 06:00 [entrez]
AID - S0920-9964(17)30123-8 [pii]
AID - 10.1016/j.schres.2017.03.008 [doi]
PST - ppublish
SO  - Schizophr Res. 2017 Dec;190:150-159. doi: 10.1016/j.schres.2017.03.008. Epub 2017 
      Mar 9.