PMID- 2828556 OWN - NLM STAT- MEDLINE DCOM- 19880315 LR - 20190828 IS - 0340-5354 (Print) IS - 0340-5354 (Linking) VI - 235 IP - 2 DP - 1987 Dec TI - Multiple sclerosis and human T-cell lymphotropic retroviruses: negative serological results in 135 German patients. PG - 102-4 AB - A total of 135 sera and 18 cerebrospinal fluid (CSF) samples from patients with multiple sclerosis (MS) were screened for antibodies to human T-cell lymphotropic virus type I (HTLV-I) and human immunodeficiency virus (HIV) by ELISA tests. None of the sera or CSF reacted with HIV antigens. Only 3 out of 135 MS sera but no MS CSF showed increased reactions in the ELISA test for HTLV-I. However, these positive reactions were classified as non-specific by immunoprecipitation. Thus no serological evidence for infection with HIV, HTLV-I, or a related retrovirus was found in the MS patients. FAU - Schneider, J AU - Schneider J AD - Deutsches Primatenzentrum, Gottingen, Federal Republic of Germany. FAU - Kitze, B AU - Kitze B FAU - Hunsmann, G AU - Hunsmann G FAU - Wendler, I AU - Wendler I FAU - Kappos, L AU - Kappos L LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Germany TA - J Neurol JT - Journal of neurology JID - 0423161 RN - 0 (Antibodies, Viral) SB - IM MH - Antibodies, Viral/*blood/cerebrospinal fluid MH - Deltaretrovirus/*immunology MH - Electrophoresis, Polyacrylamide Gel MH - Germany MH - HIV/*immunology MH - Immunologic Techniques MH - Multiple Sclerosis/blood/cerebrospinal fluid/*microbiology EDAT- 1987/12/01 00:00 MHDA- 1987/12/01 00:01 CRDT- 1987/12/01 00:00 PHST- 1987/12/01 00:00 [pubmed] PHST- 1987/12/01 00:01 [medline] PHST- 1987/12/01 00:00 [entrez] AID - 10.1007/BF00718019 [doi] PST - ppublish SO - J Neurol. 1987 Dec;235(2):102-4. doi: 10.1007/BF00718019.