PMID- 28316837
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220317
IS  - 2090-004X (Print)
IS  - 2090-0058 (Electronic)
IS  - 2090-004X (Linking)
VI  - 2017
DP  - 2017
TI  - Combination of Navigated Macular Laser Photocoagulation and Anti-VEGF Therapy: 
      Precise Treatment for Macular Edema under Dry Retinal Conditions.
PG  - 7656418
LID - 10.1155/2017/7656418 [doi]
LID - 7656418
AB  - Purpose. To compare the controllability of navigated macular laser 
      photocoagulation (MLP) in dry versus edematous retina and validate that 
      pretreatment diagnostic images can be used as basis for navigated MLP after the 
      macular edema (ME) has been resolved. Materials and Methods. Group 1 was divided 
      into subgroup 1 (dry retina MLP) and subgroup 2 (MLP in ME) for comparisons of 
      laser-burn diameters. In group 2, the areas and locations of ME before an 
      intravitreal injection of anti-VEGF (IVAV) were compared with those of recurrent 
      ME. Results. The average actual diameter as percentage of planned diameter of 
      laser burn in subgroup 1 (11 DME eyes, 6 BRVO eyes) versus subgroup 2 (5 DME 
      eyes, 8 BRVO eyes) was 115.1 +/- 9.1% versus 167.2 +/- 13.8% (based on retro-mode 
      scanning laser ophthalmoscopy), and 118.1 +/- 14.8% versus 176.1 +/- 11.6% (based on 
      OCT) (p < 0.001). In group 2 (6 DME eyes, 6 BRVO eyes), difference in mean ME 
      area before IVAV and that in recurrent edema was insignificant (p > 0.05). 
      Conclusion. The controllability of navigated MLP in dry retina is improved 
      compared to edematous retina. This study validates that pretreatment diagnostic 
      images can be used as basis for navigated MLP after the edema has been resolved.
FAU - Boiko, Ernest V
AU  - Boiko EV
AUID- ORCID: 0000-0002-7413-7478
AD  - St. Petersburg Branch of the Academician S. Fyodorov IRTC "Eye Microsurgery", 21 
      Yaroslav Gashek St., Saint Petersburg 192283, Russia; Department of 
      Ophthalmology, Mechnikov North-West State Medical University, 47 Kirochnaya St., 
      Saint Petersburg 191015, Russia; Department of Ophthalmology, Military Medical 
      Academy, 5 Klinicheskaya St., Saint Petersburg 194044, Russia.
FAU - Maltsev, Dmitrii S
AU  - Maltsev DS
AUID- ORCID: 0000-0001-6598-3982
AD  - Department of Ophthalmology, Military Medical Academy, 5 Klinicheskaya St., Saint 
      Petersburg 194044, Russia.
LA  - eng
PT  - Journal Article
DEP - 20170220
PL  - United States
TA  - J Ophthalmol
JT  - Journal of ophthalmology
JID - 101524199
PMC - PMC5338071
COIS- The authors declare that there is no conflict of interest regarding the 
      publication of this paper.
EDAT- 2017/03/21 06:00
MHDA- 2017/03/21 06:01
PMCR- 2017/02/20
CRDT- 2017/03/21 06:00
PHST- 2016/08/02 00:00 [received]
PHST- 2016/11/14 00:00 [revised]
PHST- 2017/01/04 00:00 [accepted]
PHST- 2017/03/21 06:00 [entrez]
PHST- 2017/03/21 06:00 [pubmed]
PHST- 2017/03/21 06:01 [medline]
PHST- 2017/02/20 00:00 [pmc-release]
AID - 10.1155/2017/7656418 [doi]
PST - ppublish
SO  - J Ophthalmol. 2017;2017:7656418. doi: 10.1155/2017/7656418. Epub 2017 Feb 20.