PMID- 28316844
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200929
IS  - 2090-6404 (Print)
IS  - 2090-6412 (Electronic)
IS  - 2090-6404 (Linking)
VI  - 2017
DP  - 2017
TI  - Aspergillus Pericarditis with Tamponade in a Renal Transplant Patient.
PG  - 7134586
LID - 10.1155/2017/7134586 [doi]
LID - 7134586
AB  - Aspergillus pericarditis is a rare and life-threatening infection in 
      immunosuppressed patients. It has nonspecific clinical manifestations that often 
      mimic other disease entities especially in patients who have extensive 
      comorbidities. Diagnosis is oftentimes delayed and rarely done antemortem. A high 
      degree of suspicion in immunocompromised patients is necessary for evaluation and 
      timely diagnosis. This is a case of Aspergillus pericarditis with cardiac 
      tamponade in a renal transplant patient with liver cirrhosis. Two months after 
      transplant, he developed decompensation of his cirrhosis from hepatitis C, acute 
      cellular rejection, and Kluyvera bacteremia, followed by vancomycin-resistant 
      Enterococcus faecium (VRE) bacteremia. Four months after transplant, the patient 
      presented with lethargy and fluid overload. He subsequently developed shock and 
      ventilator-dependent respiratory failure. An echocardiogram showed pericardial 
      effusion with cardiac tamponade. He had emergent pericardiocentesis that showed 
      purulent drainage. He was started on broad-spectrum antibiotics. Amphotericin B 
      was initiated when the pericardial fluid grew mold that was later identified as 
      Aspergillus fumigatus. The patient quickly decompensated and expired.
FAU - Biso, Sylvia
AU  - Biso S
AUID- ORCID: 0000-0002-2062-1037
AD  - Albert Einstein Medical Center, 5501 Old York Road, Philadelphia, PA 19141, USA.
FAU - Lekkham, Rapeepat
AU  - Lekkham R
AD  - Albert Einstein Medical Center, 5501 Old York Road, Philadelphia, PA 19141, USA.
FAU - Climaco, Antoinette
AU  - Climaco A
AD  - Albert Einstein Medical Center, 5501 Old York Road, Philadelphia, PA 19141, USA.
LA  - eng
PT  - Case Reports
DEP - 20170220
PL  - United States
TA  - Case Rep Cardiol
JT  - Case reports in cardiology
JID - 101576452
PMC - PMC5337835
COIS- The authors declare that there is no conflict of interests regarding the 
      publication of this paper.
EDAT- 2017/03/21 06:00
MHDA- 2017/03/21 06:01
PMCR- 2017/02/20
CRDT- 2017/03/21 06:00
PHST- 2016/10/13 00:00 [received]
PHST- 2017/02/02 00:00 [accepted]
PHST- 2017/03/21 06:00 [entrez]
PHST- 2017/03/21 06:00 [pubmed]
PHST- 2017/03/21 06:01 [medline]
PHST- 2017/02/20 00:00 [pmc-release]
AID - 10.1155/2017/7134586 [doi]
PST - ppublish
SO  - Case Rep Cardiol. 2017;2017:7134586. doi: 10.1155/2017/7134586. Epub 2017 Feb 20.