PMID- 28318450 OWN - NLM STAT- MEDLINE DCOM- 20180222 LR - 20181031 IS - 1541-1087 (Electronic) IS - 0731-5724 (Linking) VI - 36 IP - 3 DP - 2017 Mar-Apr TI - Repeated Sprints in Fasted State Impair Reaction Time Performance. PG - 210-217 LID - 10.1080/07315724.2016.1256795 [doi] AB - OBJECTIVE: The aim of this study was to assess the effects of 3-day Islamic intermittent fasting (3d-IF) on cognitive performance and serum levels of neurotrophic factors (brain-derived neurotrophic factor [BDNF] and vascular endothelial growth factor [VEGF]) before and after repeated sprints. METHODS: Twenty-one physically active male Muslims (29.8 +/- 5.9 years, exercising 4 +/- 1.5 times/week) were randomly assigned to one of 2 experimental sessions: the control or nonfasting session (CS) or the fasting session (FS). These 2 sessions occurred 7 days apart in a counterbalanced crossover design. In both conditions, the test was performed at the same time of day, approximately 1 hour before sunset. In the FS, the test occurred on the third day of the 3d-IF and involved the participants' performance of the following: (a) two series of 5 maximal 5-second sprints and (b) 2 cognitive tasks: One Touch Stockings (OTS) and reaction time (simple and complex RTI). RESULTS: In both conditions, the participants' reaction times during the RTI test were similar at the pre- and mid-exercise points, but postexercise, simple and complex reaction times were higher in FS compared to CS (p = 0.045, effect size [ES] = 0.21 and p = 0.006, ES = 0.41, respectively). However, OTS performance and serum levels of neurotrophic factors were not influenced by the 3d-IF. CONCLUSION: Simple and complex reaction times during the RTI test were negatively affected by the 3d-IF after 2 bouts of intensive repeated sprints. FAU - Cherif, Anissa AU - Cherif A AD - a Athlete Health and Performance Research Center, Aspetar-Orthopaedic and Sports Medicine Hospital , Doha , Qatar. AD - b Human Physiology Research Group, Faculty of Physical Education and Physiotherapy Free University of Brussel , Brussels , Belgium. FAU - Meeusen, Romain AU - Meeusen R AD - b Human Physiology Research Group, Faculty of Physical Education and Physiotherapy Free University of Brussel , Brussels , Belgium. AD - c School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University , Queensland , Australia. FAU - Farooq, Abdulaziz AU - Farooq A AD - a Athlete Health and Performance Research Center, Aspetar-Orthopaedic and Sports Medicine Hospital , Doha , Qatar. FAU - Briki, Walid AU - Briki W AD - d Qatar University, College of Arts and Sciences, Sport Science , Doha , Qatar. FAU - Fenneni, Mohamed Amine AU - Fenneni MA AD - e Laboratory of Physiology , Faculty of Medicine of Sousse, University of Sousse , Sousse , Tunisia. FAU - Chamari, Karim AU - Chamari K AD - a Athlete Health and Performance Research Center, Aspetar-Orthopaedic and Sports Medicine Hospital , Doha , Qatar. FAU - Roelands, Bart AU - Roelands B AD - b Human Physiology Research Group, Faculty of Physical Education and Physiotherapy Free University of Brussel , Brussels , Belgium. AD - f Fund for Scientific Research Flanders (FWO) , Brussels , Belgium. LA - eng PT - Journal Article PT - Randomized Controlled Trial DEP - 20170320 PL - United States TA - J Am Coll Nutr JT - Journal of the American College of Nutrition JID - 8215879 SB - IM MH - Adult MH - *Fasting MH - Humans MH - Islam MH - Male MH - Reaction Time/*physiology MH - *Running OTO - NOTNLM OT - Dietary restriction OT - anaerobic exercise OT - brain OT - cognitive task OT - memory EDAT- 2017/03/21 06:00 MHDA- 2018/02/23 06:00 CRDT- 2017/03/21 06:00 PHST- 2017/03/21 06:00 [pubmed] PHST- 2018/02/23 06:00 [medline] PHST- 2017/03/21 06:00 [entrez] AID - 10.1080/07315724.2016.1256795 [doi] PST - ppublish SO - J Am Coll Nutr. 2017 Mar-Apr;36(3):210-217. doi: 10.1080/07315724.2016.1256795. Epub 2017 Mar 20.