PMID- 28320281
OWN - NLM
STAT- MEDLINE
DCOM- 20170322
LR  - 20170322
IS  - 1608-3040 (Electronic)
IS  - 0006-2979 (Linking)
VI  - 82
IP  - 3
DP  - 2017 Mar
TI  - Cerebral Mechanisms of Hypoxic/Ischemic Postconditioning.
PG  - 392-400
LID - 10.1134/S000629791703018X [doi]
AB  - This review analyzes recent data on mechanisms of cerebral hypoxia and the 
      protective methods of hypoxic and ischemic postconditioning, as well as their 
      interrelationship with the key mechanisms responsible for neuroprotection and 
      neuroplasticity. Upregulation of expression of antiapoptotic factors and 
      neurotrophins and modulation of activity of several protein kinases and 
      transcription factors such as hypoxia-inducible factor-1 (HIF-1) are considered 
      as the most important aspects in the neuroprotective potential of 
      postconditioning. The presented information indicates substantial transformative 
      promise of the noninvasive techniques of hypoxic postconditioning as well as 
      significant similarity between the adaptive pathways activated by various 
      postconditioning methods, which are far from being fully understood.
FAU - Vetrovoy, O V
AU  - Vetrovoy OV
AD  - Pavlov Institute of Physiology, Russian Academy of Sciences, St. Petersburg, 
      199034, Russia. vov210292@yandex.ru.
FAU - Rybnikova, E A
AU  - Rybnikova EA
FAU - Samoilov, M O
AU  - Samoilov MO
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Biochemistry (Mosc)
JT  - Biochemistry. Biokhimiia
JID - 0376536
RN  - 0 (Hypoxia-Inducible Factor 1)
SB  - IM
MH  - Animals
MH  - Brain/*metabolism
MH  - Humans
MH  - Hypoxia-Inducible Factor 1/*metabolism
MH  - *Ischemic Postconditioning
MH  - *Neuronal Plasticity
EDAT- 2017/03/23 06:00
MHDA- 2017/03/23 06:01
CRDT- 2017/03/22 06:00
PHST- 2017/03/22 06:00 [entrez]
PHST- 2017/03/23 06:00 [pubmed]
PHST- 2017/03/23 06:01 [medline]
AID - BCM82030542 [pii]
AID - 10.1134/S000629791703018X [doi]
PST - ppublish
SO  - Biochemistry (Mosc). 2017 Mar;82(3):392-400. doi: 10.1134/S000629791703018X.