PMID- 28320974 OWN - NLM STAT- MEDLINE DCOM- 20170627 LR - 20171116 IS - 1347-5223 (Electronic) IS - 0009-2363 (Linking) VI - 65 IP - 5 DP - 2017 May 1 TI - Dissipation of Flonicamid in Honeysuckle and Its Transfer during Brewing Process. PG - 492-497 LID - 10.1248/cpb.c16-01015 [doi] AB - The dissipation of flonicamid in Honeysuckle and transfer pattern from Honeysuckle to its tea infusion were investigated. Flonicamid was applied on Honeysuckle crop at two dosages, 60 g of active gradient per hectare (g a.i. hm(-2)) and 180 g a.i. hm(-2) (recommended and triple the recommended) in Fenqiu, Henan Province in 2015 and 2016. Gas Chromatography-Electron Capture Detector (GC-ECD) detection methods were developed for the analysis of flonicamid residues in honeysuckles and its infusion. The recoveries in both honeysuckles and its infusion ranged from 81.5 to 101.7% with relative standard deviations (RSDs) of 3.2-9.1%. The dissipations of flonicamid in Honeysuckle were found to follow the first order kinetics with half-life ranging between 2.8 and 3.2 d. After recommended dose pesticide application, contents of flonicamid residues were lower than theoretical maximum residue limit (tMRL). Flonicamid residues can easily transfer from Honeysuckle to its tea infusion and transfer rates of flonicamid decrease with the brewing temperature reduction or the brewing times increase. These results are helpful to establish maximum residue limit and develop guidance on the appropriate and secure use of flonicamid in Honeysuckle. FAU - Wang, Yujie AU - Wang Y AD - Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College. FAU - Xue, Jian AU - Xue J AD - Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College. FAU - Jin, Hongyu AU - Jin H AD - National Institutes for Food and Drug Control. FAU - Ma, Shuangcheng AU - Ma S AD - National Institutes for Food and Drug Control. LA - eng PT - Journal Article DEP - 20170318 PL - Japan TA - Chem Pharm Bull (Tokyo) JT - Chemical & pharmaceutical bulletin JID - 0377775 RN - 0 (Pesticides) RN - 0 (Tea) RN - 25X51I8RD4 (Niacinamide) RN - 9500W2Z53J (flonicamid) SB - IM MH - Chemistry Techniques, Analytical MH - Food Contamination/*analysis MH - Lonicera/*chemistry/metabolism MH - Niacinamide/*analogs & derivatives/analysis/metabolism MH - Pesticides/*analysis/chemistry MH - Tea/*chemistry MH - Temperature OTO - NOTNLM OT - Honeysuckle OT - dissipation OT - flonicamid OT - infusion OT - transfer EDAT- 2017/03/23 06:00 MHDA- 2017/06/28 06:00 CRDT- 2017/03/22 06:00 PHST- 2017/03/23 06:00 [pubmed] PHST- 2017/06/28 06:00 [medline] PHST- 2017/03/22 06:00 [entrez] AID - 10.1248/cpb.c16-01015 [doi] PST - ppublish SO - Chem Pharm Bull (Tokyo). 2017 May 1;65(5):492-497. doi: 10.1248/cpb.c16-01015. Epub 2017 Mar 18.