PMID- 28324335
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20200929
IS  - 2190-572X (Print)
IS  - 2190-5738 (Electronic)
IS  - 2190-5738 (Linking)
VI  - 3
IP  - 5
DP  - 2013 Oct
TI  - Development of semi-defined rice straw-based medium for butanol production and 
      its kinetic study.
PG  - 353-364
LID - 10.1007/s13205-013-0120-x [doi]
AB  - Rice straw is one of the potential economic feedstock for biobutanol production 
      through ABE fermentation. However, the rice straw hydrolysate-based fermentation 
      medium needs to be supported with nutritional elements. In this study, an attempt 
      is made to optimize the rice straw hydrolysate-based fermentation medium 
      employing Clostridium acetobutylicum MTCC 481 using Taguchi design of experiments 
      (DOE) statistical model. Initially, a set of 12 nutrient components viz. 
      MgNO(3).6H(2)O, FeNO(3), NH(4)NO(3), yeast extract, PABA, biotin, PABA + biotin 
      mixture, CaCl(2), KCl, NaCl, MgSO(4) and CH(3)COONa were screened through 
      classical (one-variable-at-a-time) method. Based on the results, four components 
      (PABA, yeast extract, MgSO(4) and CH(3)COONa) were found to have significant 
      impact, and were further subjected to statistical optimization through Taguchi 
      DOE method. These experiments revealed that RSH supported with 3 g L(-1) of yeast 
      extract and 4 mg L(-1) PABA to RSH was the most optimum fermentation medium. 
      Experiments using 2 L bioreactor with this optimum fermentation medium showed 
      nearly complete utilization of soluble sugars with the production of 8.7 g L(-1) 
      of total solvents and 6 g L(-1) of butanol. The experimental data were fitted to 
      kinetic models reported in the literature to determine the kinetic parameters of 
      the fermentation process. An interesting result was revealed from this analysis 
      that the under optimized fermentation medium, the kinetic parameters for both 
      shake flask and bioreactor level were similar. This essentially means that effect 
      of scale of operation is rendered insignificant when fermentation medium is under 
      optimum conditions.
FAU - Ranjan, Amrita
AU  - Ranjan A
AD  - Centre for Energy, Indian Institute of Technology Guwahati, Guwahati, 781 039, 
      Assam, India.
FAU - Mayank, Rahul
AU  - Mayank R
AD  - Department of Chemical Engineering, Indian Institute of Technology Guwahati, 
      Guwahati, 781 039, Assam, India.
FAU - Moholkar, Vijayanand S
AU  - Moholkar VS
AD  - Centre for Energy, Indian Institute of Technology Guwahati, Guwahati, 781 039, 
      Assam, India. vmoholkar@iitg.ernet.in.
AD  - Department of Chemical Engineering, Indian Institute of Technology Guwahati, 
      Guwahati, 781 039, Assam, India. vmoholkar@iitg.ernet.in.
LA  - eng
PT  - Journal Article
DEP - 20130309
PL  - Germany
TA  - 3 Biotech
JT  - 3 Biotech
JID - 101565857
PMC - PMC3781261
OTO - NOTNLM
OT  - ABE fermentation
OT  - Biobutanol
OT  - Media development
OT  - Optimization
OT  - Rice straw hydrolysate
OT  - Taguchi DOE method
EDAT- 2013/01/01 00:00
MHDA- 2013/01/01 00:01
PMCR- 2013/03/09
CRDT- 2017/03/22 06:00
PHST- 2012/09/27 00:00 [received]
PHST- 2012/11/26 00:00 [accepted]
PHST- 2017/03/22 06:00 [entrez]
PHST- 2013/01/01 00:00 [pubmed]
PHST- 2013/01/01 00:01 [medline]
PHST- 2013/03/09 00:00 [pmc-release]
AID - 10.1007/s13205-013-0120-x [pii]
AID - 120 [pii]
AID - 10.1007/s13205-013-0120-x [doi]
PST - ppublish
SO  - 3 Biotech. 2013 Oct;3(5):353-364. doi: 10.1007/s13205-013-0120-x. Epub 2013 Mar 
      9.