PMID- 28326533 OWN - NLM STAT- MEDLINE DCOM- 20190318 LR - 20240317 IS - 1467-8624 (Electronic) IS - 0009-3920 (Print) IS - 0009-3920 (Linking) VI - 89 IP - 3 DP - 2018 May TI - Dysregulated Fear, Social Inhibition, and Respiratory Sinus Arrhythmia: A Replication and Extension. PG - e214-e228 LID - 10.1111/cdev.12774 [doi] AB - Behavioral inhibition indicates increased risk for development of social anxiety. Recent work has identified a pattern of dysregulated fear (DF), characterized by high fear in low-threat situations, that provides a more precise marker of developmental risk through early childhood. This study tested a new longitudinal sample of children (n = 124) from ages 24 to 48 months. Replicating prior findings, at 24 months, we identified a pattern of fearful behavior across contexts marked by higher fear to putatively low-threat situations. DF was associated with higher parental report of social inhibition at 24, 36, and 48 months. Extending prior findings, we observed differences in cardiac physiology during fear-eliciting situations, suggesting that the neurobiological underpinnings of DF relate to difficulty with regulation. CI - (c) 2017 The Authors. Child Development (c) 2017 Society for Research in Child Development, Inc. FAU - Buss, Kristin A AU - Buss KA AD - The Pennsylvania State University. FAU - Davis, Elizabeth L AU - Davis EL AD - University of California, Riverside. FAU - Ram, Nilam AU - Ram N AD - The Pennsylvania State University. AD - German Institute for Economic Research (DIW). FAU - Coccia, Michael AU - Coccia M AD - University of California, San Francisco. LA - eng GR - R01 HD076994/HD/NICHD NIH HHS/United States GR - P2C HD041025/HD/NICHD NIH HHS/United States GR - UL1 TR002014/TR/NCATS NIH HHS/United States GR - R24 HD041025/HD/NICHD NIH HHS/United States GR - R01 MH075750/MH/NIMH NIH HHS/United States GR - UL1 TR000127/TR/NCATS NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't DEP - 20170321 PL - United States TA - Child Dev JT - Child development JID - 0372725 SB - IM MH - Child Behavior/*physiology MH - Child, Preschool MH - Fear/*physiology MH - Female MH - Humans MH - *Inhibition, Psychological MH - Longitudinal Studies MH - Male MH - Respiratory Sinus Arrhythmia/*physiology MH - *Self-Control MH - *Social Behavior PMC - PMC5608616 MID - NIHMS848037 EDAT- 2017/03/23 06:00 MHDA- 2019/03/19 06:00 PMCR- 2019/05/01 CRDT- 2017/03/23 06:00 PHST- 2017/03/23 06:00 [pubmed] PHST- 2019/03/19 06:00 [medline] PHST- 2017/03/23 06:00 [entrez] PHST- 2019/05/01 00:00 [pmc-release] AID - 10.1111/cdev.12774 [doi] PST - ppublish SO - Child Dev. 2018 May;89(3):e214-e228. doi: 10.1111/cdev.12774. Epub 2017 Mar 21.