PMID- 28330444
OWN - NLM
STAT- MEDLINE
DCOM- 20171226
LR  - 20220408
IS  - 1471-2431 (Electronic)
IS  - 1471-2431 (Linking)
VI  - 17
IP  - 1
DP  - 2017 Mar 22
TI  - Incidence and time trends of type 2 diabetes mellitus in youth aged 5-19 years: a 
      population-based registry in Zhejiang, China, 2007 to 2013.
PG  - 85
LID - 10.1186/s12887-017-0834-8 [doi]
LID - 85
AB  - BACKGROUND: The incidence of type 2 diabetes mellitus (T2DM) has been increasing 
      globally over the past two decades in children and adolescents. There are 
      currently a dearth of comprehensive population-based estimates of T2DM incidence 
      and time trends in Chinese youth. METHODS: A population-based diabetes registry 
      system in 30 representative districts in Zhejiang has been established for 
      diabetes surveillance. All newly cases diagnosed by physicians in local hospitals 
      and wards were registered using the registry system through web services and 
      direct network report. The data were primarily abstracted from medical records in 
      hospitals and wards. Annual incidence rates and their 95% confidence intervals 
      (CIs) by age groups and sex were calculated per 100 000 person-years. Poisson 
      regression models were applied to assess the effects of diagnosis year, age 
      groups, sex and residence area on T2DM incidence and to examine the average 
      annual percentage change in incidence. RESULTS: There were 392 newly diagnosed 
      cases of T2DM (210 boys and 182 girls) over the study period. The mean annual 
      age-standardized incidence was 1.96/100 000 person-years (95% CIs: 1.85-2.08). No 
      statistically significant difference in incidence was found between boys and 
      girls. However, the risk for T2DM was 1.49 times higher in urban area than in 
      rural area. Besides, the mean annual incidence in youth increased with age. The 
      age-standardized incidence was about 5 times higher in 2013 than in 2007. Steep 
      rising incidence was observed, with an average annual increase of 26.6% in youth 
      aged 10-19 years. CONCLUSIONS: The incidence of T2DM in children and adolescents 
      was low in Zhejiang relative to other countries, whereas it increased markedly 
      over the study period. Preventive strategies for T2DM are necessary in pediatric 
      population.
FAU - Wu, Haibin
AU  - Wu H
AD  - Department of NCDs Control and Prevention, Zhejiang Provincial Center for Disease 
      Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China.
FAU - Zhong, Jieming
AU  - Zhong J
AD  - Department of NCDs Control and Prevention, Zhejiang Provincial Center for Disease 
      Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China.
FAU - Yu, Min
AU  - Yu M
AD  - Department of NCDs Control and Prevention, Zhejiang Provincial Center for Disease 
      Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China.
FAU - Wang, Hao
AU  - Wang H
AD  - Department of NCDs Control and Prevention, Zhejiang Provincial Center for Disease 
      Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China.
FAU - Gong, Weiwei
AU  - Gong W
AD  - Department of NCDs Control and Prevention, Zhejiang Provincial Center for Disease 
      Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China.
FAU - Pan, Jin
AU  - Pan J
AD  - Department of NCDs Control and Prevention, Zhejiang Provincial Center for Disease 
      Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China.
FAU - Fei, Fangrong
AU  - Fei F
AD  - Department of NCDs Control and Prevention, Zhejiang Provincial Center for Disease 
      Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China.
FAU - Wang, Meng
AU  - Wang M
AD  - Department of NCDs Control and Prevention, Zhejiang Provincial Center for Disease 
      Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China.
FAU - Yang, Li
AU  - Yang L
AD  - Zhejiang Provincial Center for cardio-cerebrovascular diseases control and 
      prevention, Zhejiang Hospital, 12 Lingyin Road, Hangzhou, 310013, China.
FAU - Hu, Ruying
AU  - Hu R
AD  - Department of NCDs Control and Prevention, Zhejiang Provincial Center for Disease 
      Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China. 
      ryhu@cdc.zj.cn.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20170322
PL  - England
TA  - BMC Pediatr
JT  - BMC pediatrics
JID - 100967804
SB  - IM
MH  - Adolescent
MH  - Age Distribution
MH  - Child
MH  - Child, Preschool
MH  - China/epidemiology
MH  - Diabetes Mellitus, Type 2/*epidemiology/etiology
MH  - Female
MH  - Humans
MH  - Incidence
MH  - Male
MH  - Poisson Distribution
MH  - Registries
MH  - Regression Analysis
MH  - Residence Characteristics
MH  - Risk Factors
MH  - Sex Distribution
MH  - Young Adult
PMC - PMC5361693
OTO - NOTNLM
OT  - Children and adolescents
OT  - China
OT  - Epidemiology
OT  - Type 2 diabetes mellitus
EDAT- 2017/03/24 06:00
MHDA- 2017/12/27 06:00
PMCR- 2017/03/22
CRDT- 2017/03/24 06:00
PHST- 2015/11/04 00:00 [received]
PHST- 2017/03/08 00:00 [accepted]
PHST- 2017/03/24 06:00 [entrez]
PHST- 2017/03/24 06:00 [pubmed]
PHST- 2017/12/27 06:00 [medline]
PHST- 2017/03/22 00:00 [pmc-release]
AID - 10.1186/s12887-017-0834-8 [pii]
AID - 834 [pii]
AID - 10.1186/s12887-017-0834-8 [doi]
PST - epublish
SO  - BMC Pediatr. 2017 Mar 22;17(1):85. doi: 10.1186/s12887-017-0834-8.