PMID- 28341544
OWN - NLM
STAT- MEDLINE
DCOM- 20180302
LR  - 20181202
IS  - 1876-4738 (Electronic)
IS  - 0914-5087 (Linking)
VI  - 70
IP  - 4
DP  - 2017 Oct
TI  - Echocardiographic assessment of right ventricular function in routine practice: 
      Which parameters are useful to predict one-year outcome in advanced heart failure 
      patients with dilated cardiomyopathy?
PG  - 316-322
LID - S0914-5087(17)30061-8 [pii]
LID - 10.1016/j.jjcc.2017.02.007 [doi]
AB  - BACKGROUND: Right ventricular (RV) function has recently gained attention as a 
      prognostic predictor of outcome even in patients who have left-sided heart 
      failure. Since several conventional echocardiographic parameters of RV systolic 
      function have been proposed, our aim was to determine if any of these parameters 
      (tricuspid annular plane systolic excursion: TAPSE, tissue Doppler derived 
      systolic tricuspid annular motion velocity: S', fractional area change: FAC) are 
      associated with outcome in advanced heart failure patients with dilated 
      cardiomyopathy (DCM). METHODS: We retrospectively enrolled 68 DCM patients, who 
      were New York Heart Association (NYHA) Class III or IV and had a left ventricular 
      (LV) ejection fraction <35%. All patients were undergoing evaluation for heart 
      transplantation or management of heart failure. Primary outcomes were defined as 
      LV assist device implantation or cardiac death within one year. RESULTS: 
      Thirty-nine events occurred (5 deaths, 32 LV assist devices implanted). 
      Univariate analysis showed that age, systolic blood pressure, heart rate, NYHA 
      functional class IV, plasma brain natriuretic peptide concentration, intravenous 
      inotrope use, left atrial volume index, and FAC were associated with outcome, 
      whereas TAPSE and S' were not. Receiver-operating characteristic curve analysis 
      showed that the optimal FAC cut-off value to identify patients with an event was 
      <26.7% (area under the curve=0.74). The event-free rate determined by 
      Kaplan-Meier analysis was significantly higher in patients with FAC>/=26.7% than in 
      those with FAC<26.7% (log-lank, p=0.0003). Moreover, the addition of FAC<26.7% 
      improved the prognostic utility of a model containing clinical variables and 
      conventional echocardiographic indexes. CONCLUSIONS: FAC may provide better 
      prognostic information than TAPSE or S' in advanced heart failure patients with 
      DCM.
CI  - Copyright (c) 2017 Japanese College of Cardiology. Published by Elsevier Ltd. All 
      rights reserved.
FAU - Kawata, Takayuki
AU  - Kawata T
AD  - Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan. 
      Electronic address: DQH07724@nifty.ne.jp.
FAU - Daimon, Masao
AU  - Daimon M
AD  - Department of Clinical Laboratory, The University of Tokyo, Tokyo, Japan.
FAU - Kimura, Koichi
AU  - Kimura K
AD  - Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
FAU - Nakao, Tomoko
AU  - Nakao T
AD  - Department of Clinical Laboratory, The University of Tokyo, Tokyo, Japan.
FAU - Lee, Seitetsu L
AU  - Lee SL
AD  - Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
FAU - Hirokawa, Megumi
AU  - Hirokawa M
AD  - Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
FAU - Kato, Tomoko S
AU  - Kato TS
AD  - Department of Cardiovascular Surgery, Juntendo University School of Medicine, 
      Tokyo, Japan.
FAU - Watanabe, Masafumi
AU  - Watanabe M
AD  - Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
FAU - Yatomi, Yutaka
AU  - Yatomi Y
AD  - Department of Clinical Laboratory, The University of Tokyo, Tokyo, Japan.
FAU - Komuro, Issei
AU  - Komuro I
AD  - Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan.
LA  - eng
PT  - Journal Article
DEP - 20170321
PL  - Netherlands
TA  - J Cardiol
JT  - Journal of cardiology
JID - 8804703
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
SB  - IM
MH  - Adult
MH  - Cardiomyopathy, Dilated/blood/*diagnostic imaging/physiopathology
MH  - Echocardiography, Doppler
MH  - Female
MH  - Heart Failure/blood/*diagnostic imaging/physiopathology
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Male
MH  - Middle Aged
MH  - Natriuretic Peptide, Brain/blood
MH  - Prognosis
MH  - ROC Curve
MH  - Systole
MH  - Ventricular Function, Left/physiology
MH  - Ventricular Function, Right/*physiology
MH  - Young Adult
OTO - NOTNLM
OT  - Dilated cardiomyopathy
OT  - Echocardiography
OT  - Prognosis
OT  - Right ventricular function
EDAT- 2017/03/28 06:00
MHDA- 2018/03/03 06:00
CRDT- 2017/03/26 06:00
PHST- 2016/10/07 00:00 [received]
PHST- 2017/01/03 00:00 [revised]
PHST- 2017/02/02 00:00 [accepted]
PHST- 2017/03/28 06:00 [pubmed]
PHST- 2018/03/03 06:00 [medline]
PHST- 2017/03/26 06:00 [entrez]
AID - S0914-5087(17)30061-8 [pii]
AID - 10.1016/j.jjcc.2017.02.007 [doi]
PST - ppublish
SO  - J Cardiol. 2017 Oct;70(4):316-322. doi: 10.1016/j.jjcc.2017.02.007. Epub 2017 Mar 
      21.