PMID- 28345365 OWN - NLM STAT- MEDLINE DCOM- 20170731 LR - 20170731 IS - 1651-2006 (Electronic) IS - 1401-7431 (Linking) VI - 51 IP - 3 DP - 2017 Jun TI - Atrioventricular nodal ablation in patients with resynchronization therapy and atrial fibrillation - long term results. PG - 138-142 LID - 10.1080/14017431.2017.1307443 [doi] AB - OBJECTIVES: Atrioventricular nodal ablation (AVNA) is recommended for patients (pts) with cardiac resynchronization therapy (CRT) having atrial fibrillation (AF) and incomplete ventricular capture (Class IIa, level B). AVNA reduces mortality and improves the New York Heart Association (NYHA) functional class during intermediate term follow-up. The objectives were to study the long-term outcome regarding quality of life (QoL) and survival of our CRT pts after AVNA. DESIGN: 37 CRT-pts undergoing AVNA due to inadequate biventricular pacing were included in the study. Data were retrospectively obtained from clinical records and through telephone interviews. RESULTS: Twenty pts died during the follow-up period of average 30.6 +/- 24 months. After AVNA the ventricular capture improved significantly from 68.4 +/- 23% to 98.5 +/- 2% (p < 0.001). A significant and sustained improvement of average 0.3 +/- 0.5 (p = 0.001) in NYHA functional class was found. Additionally a large percentage of pts discontinued taking rate reducing drugs with potential severe side effects. CONCLUSION: AVNA in CRT pts was safe and effective. The treatment resulted in a sustained improvement in QoL, including long-term improvement in NYHA functional class. FAU - Aune, Arleen AU - Aune A AD - a Department for Cardiology , Haukeland University Hospital , Bergen , Norway. FAU - Faerestrand, Svein AU - Faerestrand S AD - a Department for Cardiology , Haukeland University Hospital , Bergen , Norway. AD - b Department of Clinical Science , University of Bergen , Norway. FAU - Hoff, Per Ivar AU - Hoff PI AD - a Department for Cardiology , Haukeland University Hospital , Bergen , Norway. FAU - Schuster, Peter AU - Schuster P AD - a Department for Cardiology , Haukeland University Hospital , Bergen , Norway. AD - b Department of Clinical Science , University of Bergen , Norway. LA - eng PT - Journal Article PT - Observational Study DEP - 20170327 PL - England TA - Scand Cardiovasc J JT - Scandinavian cardiovascular journal : SCJ JID - 9708377 SB - IM MH - Aged MH - Atrial Fibrillation/diagnosis/mortality/physiopathology/*surgery MH - Atrioventricular Node/physiopathology/*surgery MH - *Cardiac Resynchronization Therapy/adverse effects/mortality MH - Catheter Ablation/adverse effects/*methods/mortality MH - Female MH - Heart Failure/diagnosis/mortality/physiopathology/*therapy MH - Humans MH - Interviews as Topic MH - Male MH - Medical Records MH - Middle Aged MH - Norway MH - Quality of Life MH - Recovery of Function MH - Retrospective Studies MH - Risk Factors MH - Survival Analysis MH - Time Factors MH - Treatment Outcome OTO - NOTNLM OT - AV nodal ablation OT - Atrial Fibrillation OT - Chronic Heart Failure OT - Quality of Life OT - Resynchronization therapy EDAT- 2017/03/28 06:00 MHDA- 2017/08/02 06:00 CRDT- 2017/03/28 06:00 PHST- 2017/03/28 06:00 [pubmed] PHST- 2017/08/02 06:00 [medline] PHST- 2017/03/28 06:00 [entrez] AID - 10.1080/14017431.2017.1307443 [doi] PST - ppublish SO - Scand Cardiovasc J. 2017 Jun;51(3):138-142. doi: 10.1080/14017431.2017.1307443. Epub 2017 Mar 27.