PMID- 28345830 OWN - NLM STAT- Publisher LR - 20191120 IS - 2476-762X (Electronic) IS - 1513-7368 (Print) IS - 1513-7368 (Linking) VI - 18 IP - 2 DP - 2017 Feb 1 TI - Histopathologic Evolution of Urothelial Carcinoma Recurrence in Transurethral Resection of the Urinary Bladder:35 Consecutive Cases And Literature Review. PG - 459-463 AB - Background: Urothelial carcinoma (UC) is the malignancy most frequently encountered in the urinary bladder.The primary aim of this study was to make a reappraisal of histopathologic features, recurrence and progression. Materials and Methods: The records of cases consecutively diagnosed with UC in the state hospital pathology laboratory were collected. Cases were classified according to age, gender, histologic grade, pathologic staging [primary Tumor (pT)] ,tumor configuration, primary or recurrent status, and progression. Results: A total of 35 (29 male and 6 female) cases were examined. The mean age was 68.9 years with a male-to-female incidence ratio of 4.8:1. Low-grade UCs accounted for 20 (57.1%) and high-grade for 15 (42.9%). A papillary pattern was observed in 80% of the UCs, classified into the following pathological stages: 11 (31.4%) pTa, 22 (62.9%) pT1, and 2 (5.9%) pT2 cases. Eleven patients progressed to a higher stage (pT1 to pT2), and three cases from low to higher grade. We analyzed results for 26 (74.3%) cases aged 65 years or older. Conclusions: UCs have a great tendency for recurrence but potentially may be amenable to effective local or systemic treatments. CI - Creative Commons Attribution License FAU - Koyuncuer, Ali AU - Koyuncuer A AD - Department of Pathology, Antakya State Hospital, Hatay, Turkey. Email: alikoyuncuer@hotmail.com LA - eng PT - Journal Article DEP - 20170201 PL - Thailand TA - Asian Pac J Cancer Prev JT - Asian Pacific journal of cancer prevention : APJCP JID - 101130625 PMC - PMC5454743 OTO - NOTNLM OT - Bladder OT - carcinoma OT - grade OT - stage OT - progression OT - recurrence OT - urothelial EDAT- 2017/03/28 06:00 MHDA- 2017/03/28 06:00 PMCR- 2017/03/01 CRDT- 2017/03/28 06:00 PHST- 2017/03/28 06:00 [pubmed] PHST- 2017/03/28 06:00 [medline] PHST- 2017/03/28 06:00 [entrez] PHST- 2017/03/01 00:00 [pmc-release] AID - APJCP-18-459 [pii] AID - 10.22034/APJCP.2017.18.2.459 [doi] PST - epublish SO - Asian Pac J Cancer Prev. 2017 Feb 1;18(2):459-463. doi: 10.22034/APJCP.2017.18.2.459.