PMID- 28350484
OWN - NLM
STAT- MEDLINE
DCOM- 20170828
LR  - 20181202
IS  - 1546-3141 (Electronic)
IS  - 0361-803X (Linking)
VI  - 208
IP  - 6
DP  - 2017 Jun
TI  - Variability in Radiation Dose From Repeat Identical CT Examinations: Longitudinal 
      Analysis of 2851 Patients Undergoing 12,635 Thoracoabdominal CT Scans in an 
      Academic Health System.
PG  - 1285-1296
LID - 10.2214/AJR.16.17070 [doi]
AB  - OBJECTIVE: The purpose of this study was to conduct longitudinal analyses of 
      radiation dose data from adult patients undergoing clinically indicated, repeat 
      identical thoracoabdominal CT examinations. MATERIALS AND METHODS: Radiation dose 
      data were electronically collected from 2851 subjects undergoing 12,635 repeat 
      identical CT scans (mean number of scans per patient, 4.8; range, 2-33) in one 
      health system. Included CT protocols were chest-abdomen-pelvis with contrast 
      administration (n = 4621 CT studies of 1064 patients), abdomen-pelvis with 
      contrast administration (n = 876 CT studies of 261 patients), renal stone (n = 
      1053 CT studies of 380 patients), and chest (n = 6085 CT studies of 1146 
      patients) without contrast administration. A radiation-tracking software 
      infrastructure was adopted to extract data from DICOM headers in PACS. 
      Size-specific dose estimate (SSDE) was calculated. RESULTS: A trend was observed 
      toward global reduction in SSDE values with all protocols investigated 
      (chest-abdomen-pelvis slope, -1.78; abdomen-pelvis slope, -0.82; renal stone 
      slope, -0.83; chest slope, -0.47; p < 0.001 for all comparisons). The 
      intraindividual analyses of radiation dose distribution showed widespread 
      variability in SSDE values across the four protocols investigated 
      (chest-abdomen-pelvis mean coefficient of variance, 14.02 mGy; abdomen-pelvis 
      mean coefficient of variance, 10.26 mGy; renal stone mean coefficient of 
      variance, 34.18 mGy; chest mean coefficient of variance, 6.74 mGy). CONCLUSION: 
      Although there is a trend toward global reduction in radiation doses, this study 
      showed widespread variability in the radiation dose that each patient undergoing 
      identical repeat thoracoabdominal CT protocols absorbs. These data may provide a 
      foundation for the future development of best-practice guidelines for 
      patient-specific radiation dose monitoring.
FAU - Mileto, Achille
AU  - Mileto A
AD  - 1 Department of Radiology, University of Washington School of Medicine, Box 
      357115, 1959 NE Pacific St, Seattle, WA 98195.
AD  - 2 Department of Radiology, Duke University Medical Center, Durham, NC.
FAU - Nelson, Rendon C
AU  - Nelson RC
FAU - Larson, Douglas G
AU  - Larson DG
FAU - Samei, Ehsan
AU  - Samei E
FAU - Wilson, Joshua M
AU  - Wilson JM
FAU - Christianson, Olav
AU  - Christianson O
FAU - Marin, Daniele
AU  - Marin D
FAU - Boll, Daniel T
AU  - Boll DT
AD  - 2 Department of Radiology, Duke University Medical Center, Durham, NC.
AD  - 3 Department of Radiology, University Hospital of Basel, Basel, Switzerland.
LA  - eng
PT  - Journal Article
DEP - 20170328
PL  - United States
TA  - AJR Am J Roentgenol
JT  - AJR. American journal of roentgenology
JID - 7708173
SB  - IM
MH  - Academic Medical Centers/*statistics & numerical data
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Female
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - North Carolina/epidemiology
MH  - *Radiation Dosage
MH  - Radiation Exposure/*statistics & numerical data
MH  - Radiography, Abdominal/*statistics & numerical data
MH  - Radiography, Thoracic/*statistics & numerical data
MH  - Radiometry/statistics & numerical data
MH  - Reproducibility of Results
MH  - Sensitivity and Specificity
MH  - Tomography, X-Ray Computed/*statistics & numerical data
MH  - Young Adult
OTO - NOTNLM
OT  - CT
OT  - longitudinal analysis
OT  - radiation dose
OT  - size-specific dose estimate
OT  - variability
EDAT- 2017/03/30 06:00
MHDA- 2017/08/29 06:00
CRDT- 2017/03/29 06:00
PHST- 2017/03/30 06:00 [pubmed]
PHST- 2017/08/29 06:00 [medline]
PHST- 2017/03/29 06:00 [entrez]
AID - 10.2214/AJR.16.17070 [doi]
PST - ppublish
SO  - AJR Am J Roentgenol. 2017 Jun;208(6):1285-1296. doi: 10.2214/AJR.16.17070. Epub 
      2017 Mar 28.