PMID- 28357679
OWN - NLM
STAT- MEDLINE
DCOM- 20180109
LR  - 20220409
IS  - 1573-2649 (Electronic)
IS  - 0962-9343 (Print)
IS  - 0962-9343 (Linking)
VI  - 26
IP  - 8
DP  - 2017 Aug
TI  - Changes in quality of life after elective surgery: an observational study 
      comparing two measures.
PG  - 2093-2102
LID - 10.1007/s11136-017-1560-2 [doi]
AB  - PURPOSE: Our main objective was to compare the change in a validated quality of 
      life measure to a global assessment measure. The secondary objectives were to 
      estimate the minimum clinically important difference (MCID) and to describe the 
      change in quality of life by surgical specialty. METHODS: This prospective cohort 
      study included 7902 adult patients undergoing elective surgery. Changes in the 
      Veterans RAND 12-Item Health Survey (VR-12), composed of a physical component 
      summary (PCS) and a mental component summary (MCS), were calculated using 
      preoperative and postoperative questionnaires. The latter also contained a global 
      assessment question for quality of life. We compared PCS and MCS to the global 
      assessment using descriptive statistics and weighted kappa. MCID was calculated 
      using an anchor-based approach. Analyses were pre-specified and registered 
      (NCT02771964). RESULTS: By the change in VR-12 scores, an equal proportion of 
      patients experienced improvement and deterioration in quality of life (28% for 
      PCS, 25% for MCS). In contrast, by the global assessment measure, 61% reported 
      improvement, while only 10% reported deterioration. Agreement with the global 
      assessment was slight for both PCS (kappa = 0.20, 57% matched) and MCS 
      (kappa = 0.10, 54% matched). The MCID for the overall VR-12 score was 
      approximately 2.5 points. Patients undergoing orthopedic surgery showed the most 
      improvement in quality of life measures, while patients undergoing 
      gastrointestinal/hepatobiliary or urologic surgery showed the most deterioration. 
      CONCLUSIONS: Subjective global quality of life report does not agree well with a 
      validated quality of life instrument, perhaps due to patient over-optimism.
FAU - Kronzer, Vanessa L
AU  - Kronzer VL
AD  - Department of Anesthesia, Washington University School of Medicine, 660 South 
      Euclid Avenue, Campus Box 8054, Saint Louis, MO, 63110, USA.
FAU - Jerry, Michelle R
AU  - Jerry MR
AD  - Department of Biostatistics, University of Michigan, 534 Canton Street, Canton, 
      MI, 48188, USA.
FAU - Ben Abdallah, Arbi
AU  - Ben Abdallah A
AD  - Department of Anesthesia, Washington University School of Medicine, 660 South 
      Euclid Avenue, Campus Box 8054, Saint Louis, MO, 63110, USA.
FAU - Wildes, Troy S
AU  - Wildes TS
AD  - Department of Anesthesia, Washington University School of Medicine, 660 South 
      Euclid Avenue, Campus Box 8054, Saint Louis, MO, 63110, USA.
FAU - McKinnon, Sherry L
AU  - McKinnon SL
AD  - Department of Anesthesia, Washington University School of Medicine, 660 South 
      Euclid Avenue, Campus Box 8054, Saint Louis, MO, 63110, USA.
FAU - Sharma, Anshuman
AU  - Sharma A
AD  - Department of Anesthesia, Washington University School of Medicine, 660 South 
      Euclid Avenue, Campus Box 8054, Saint Louis, MO, 63110, USA.
FAU - Avidan, Michael S
AU  - Avidan MS
AUID- ORCID: 0000-0002-7489-3134
AD  - Department of Anesthesia, Washington University School of Medicine, 660 South 
      Euclid Avenue, Campus Box 8054, Saint Louis, MO, 63110, USA. 
      avidanm@anest.wustl.edu.
LA  - eng
SI  - ClinicalTrials.gov/NCT02771964
GR  - TL1 TR000449/TR/NCATS NIH HHS/United States
GR  - UL1 TR000448/TR/NCATS NIH HHS/United States
GR  - UH2 AG050312/AG/NIA NIH HHS/United States
PT  - Journal Article
DEP - 20170329
PL  - Netherlands
TA  - Qual Life Res
JT  - Quality of life research : an international journal of quality of life aspects of 
      treatment, care and rehabilitation
JID - 9210257
SB  - IM
MH  - Cohort Studies
MH  - *Disability Evaluation
MH  - Elective Surgical Procedures/*psychology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Quality of Life/*psychology
MH  - Surveys and Questionnaires
MH  - Treatment Outcome
PMC - PMC6309881
MID - NIHMS999111
OTO - NOTNLM
OT  - Elective surgical procedures
OT  - Minimum clinically important difference (MCID)
OT  - Outcome assessment
OT  - Patient-reported outcomes
OT  - Quality of life
COIS- Conflicts of interest: The authors declare that they have no conflict of 
      interest.
EDAT- 2017/03/31 06:00
MHDA- 2018/01/10 06:00
PMCR- 2018/12/28
CRDT- 2017/03/31 06:00
PHST- 2017/03/21 00:00 [accepted]
PHST- 2017/03/31 06:00 [pubmed]
PHST- 2018/01/10 06:00 [medline]
PHST- 2017/03/31 06:00 [entrez]
PHST- 2018/12/28 00:00 [pmc-release]
AID - 10.1007/s11136-017-1560-2 [pii]
AID - 10.1007/s11136-017-1560-2 [doi]
PST - ppublish
SO  - Qual Life Res. 2017 Aug;26(8):2093-2102. doi: 10.1007/s11136-017-1560-2. Epub 
      2017 Mar 29.