PMID- 28360240
OWN - NLM
STAT- MEDLINE
DCOM- 20171218
LR  - 20181113
IS  - 2044-6055 (Electronic)
IS  - 2044-6055 (Linking)
VI  - 7
IP  - 3
DP  - 2017 Mar 29
TI  - Meta-analysis of the effectiveness of psychological and medical treatments for 
      binge-eating disorder (MetaBED): study protocol.
PG  - e013655
LID - 10.1136/bmjopen-2016-013655 [doi]
LID - e013655
AB  - INTRODUCTION: Binge-eating disorder (BED) was included as its own diagnostic 
      entity in the Fifth Edition of the Diagnostic and Statistical Manual of Mental 
      Disorders (DSM-5). An increasing number of treatment studies have been published, 
      but an up-to-date comprehensive meta-analysis on diverse treatment approaches for 
      BED is lacking. In an updated and extension of a previous meta-analysis, the 
      goals of this study are to assess the short-term and long-term effectiveness of 
      psychological and medical treatments for BED. METHODS AND ANALYSIS: We will 
      search bibliographic databases and study registries, including manual searches 
      for studies published before January 2016. The search strategy will include terms 
      relating to binge eating and diverse forms of psychological and medical 
      interventions. Language will be restricted to English. The studies included will 
      be treatment studies, that is, randomised-controlled trials, and non-randomised 
      and non-controlled studies, for individuals with BED (DSM-IV or DSM-5), and 
      studies that provided a pre-treatment and at least one post-treatment or 
      follow-up assessment of binge eating. The primary outcomes will be the number of 
      binge-eating episodes, abstinence from binge eating and diagnosis of BED at 
      post-treatment and/or follow-up(s), and changes from pre-treatment to 
      post-treatment and/or follow-up(s). Likewise, as secondary outcomes, eating 
      disorder and general psychopathology, quality of life, and body weight will be 
      analysed and adverse events and treatment drop-out will be examined. Study 
      search, selection and data extraction, including risk of bias assessment, will be 
      independently performed by 2 reviewers and consensus will be sought. Moderator 
      analyses will be conducted, and equity aspects will be considered. Sensitivity 
      analyses will be conducted to determine the robustness of the results. ETHICS AND 
      DISSEMINATION: Ethical approval is not required for this meta-analysis. Published 
      in a peer-reviewed journal and disseminated electronically and in print, this 
      meta-analysis will form the basis of the renewal of the German evidence-based S3 
      Guidelines of Diagnosis and Treatment of Eating Disorders, specifically BED. 
      TRIAL REGISTRATION NUMBER: CRD42016043604.
CI  - Published by the BMJ Publishing Group Limited. For permission to use (where not 
      already granted under a licence) please go to 
      http://www.bmj.com/company/products-services/rights-and-licensing/.
FAU - Hilbert, Anja
AU  - Hilbert A
AD  - Department of Medical Psychology and Medical Sociology, Department of 
      Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, 
      Leipzig, Germany.
FAU - Petroff, David
AU  - Petroff D
AD  - Clinical Trial Center Leipzig, University of Leipzig, Leipzig, Germany.
FAU - Herpertz, Stephan
AU  - Herpertz S
AD  - Department of Psychosomatic Medicine, LWL-University Clinic, Ruhr-University 
      Bochum, Bochum, Germany.
FAU - Kersting, Anette
AU  - Kersting A
AD  - Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig 
      Medical Center, Leipzig, Germany.
FAU - Pietrowsky, Reinhard
AU  - Pietrowsky R
AD  - Department of Clinical Psychology, Institute of Experimental Psychology, 
      University of Dusseldorf, Dusseldorf, Germany.
FAU - Tuschen-Caffier, Brunna
AU  - Tuschen-Caffier B
AD  - Department of Psychology, University of Freiburg, Freiburg, Germany.
FAU - Vocks, Silja
AU  - Vocks S
AD  - Department of Clinical Psychology and Psychotherapy, Institute of Psychology, 
      University of Osnabruck, Osnabruck, Germany.
FAU - Schmidt, Ricarda
AU  - Schmidt R
AD  - Department of Medical Psychology and Medical Sociology, Department of 
      Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, 
      Leipzig, Germany.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20170329
PL  - England
TA  - BMJ Open
JT  - BMJ open
JID - 101552874
SB  - IM
MH  - Bariatric Surgery/methods
MH  - Binge-Eating Disorder/*therapy
MH  - Clinical Trials as Topic
MH  - Data Collection/methods
MH  - Humans
MH  - Information Dissemination/methods
MH  - Psychotherapy/methods
MH  - Selection Bias
MH  - Self Care
MH  - Treatment Outcome
MH  - Weight Loss
PMC - PMC5372140
OTO - NOTNLM
OT  - bariatric surgery
OT  - binge-eating disorder
OT  - meta-analysis
OT  - pharmacotherapy
OT  - psychotherapy
OT  - treatment
COIS- Competing interests: The authors will give presentations on this topic, with 
      honoraria and travel costs covered by organisers.
EDAT- 2017/04/01 06:00
MHDA- 2017/12/19 06:00
PMCR- 2017/03/29
CRDT- 2017/04/01 06:00
PHST- 2017/04/01 06:00 [entrez]
PHST- 2017/04/01 06:00 [pubmed]
PHST- 2017/12/19 06:00 [medline]
PHST- 2017/03/29 00:00 [pmc-release]
AID - bmjopen-2016-013655 [pii]
AID - 10.1136/bmjopen-2016-013655 [doi]
PST - epublish
SO  - BMJ Open. 2017 Mar 29;7(3):e013655. doi: 10.1136/bmjopen-2016-013655.