PMID- 28360811
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231112
IS  - 1300-0667 (Print)
IS  - 1309-4866 (Electronic)
IS  - 1300-0667 (Linking)
VI  - 53
IP  - 4
DP  - 2016 Dec
TI  - Evaluation of the Relationship between Brain-Derived Neurotropic Factor Levels 
      and the Stroop Interference Effect in Children with Attention-Deficit 
      Hyperactivity Disorder.
PG  - 348-352
LID - 10.5152/npa.2016.10234 [doi]
AB  - INTRODUCTION: Brain-derived neurotropic factor (BDNF) has been suggested to play 
      a role in the pathogenesis of attention-deficit hyperactivity disorder (ADHD). In 
      addition, impairment in executive functions has been reported in children with 
      ADHD. This study investigated the presence of a relationship between Stroop test 
      scores and BDNF levels in children with ADHD. METHODS: The study was conducted in 
      the Department of Child Psychiatry at Dicle University. The study included 49 
      children between 6 and 15 years of age (M/F: 42/7), who were diagnosed with ADHD 
      according to DSM-IV, and who did not receive previous therapy. Similar in terms 
      of age and gender to the ADHD group, 40 children were selected in the control 
      group. The Kiddie Schedule for Affective Disorders and Schizophrenia, Present and 
      Lifetime version was administered to all participants. Parents and teachers were 
      administered Turgay DSM-IV-based Child and Adolescent Behavior Disorders 
      Screening and Rating Scale to measure symptom severity in children with ADHD. 
      Children with ADHD underwent the Stroop test. BDNF levels were evaluated in serum 
      by ELISA. RESULTS: The ADHD and control groups did not differ in terms of BDNF 
      levels. BDNF levels did not differ between ADHD subtypes. There was also no 
      relationship between the Stroop test interference scores and BDNF levels. 
      CONCLUSION: The findings of the present study are in line with those in studies 
      that demonstrated no significant role of BDNF in the pathogenesis of ADHD.
FAU - Simsek, Seref
AU  - Simsek S
AD  - Department of Child Psychiatry, Dicle University School of Medicine, Diyarbakir, 
      Turkey.
FAU - Gencoglan, Salih
AU  - Gencoglan S
AD  - Department of Child Psychiatry, Yuzuncu Yil University School of Medicine, Van, 
      Turkey.
FAU - Yuksel, Tugba
AU  - Yuksel T
AD  - Department of Child Psychiatry, Dicle University School of Medicine, Diyarbakir, 
      Turkey.
FAU - Kaplan, Ibrahim
AU  - Kaplan I
AD  - Department of Biochemistry, Dicle University School of Medicine, Diyarbakir, 
      Turkey.
FAU - Aktas, Huseyin
AU  - Aktas H
AD  - Department of Child Psychiatry, Dicle University School of Medicine, Diyarbakir, 
      Turkey.
FAU - Alaca, Rumeysa
AU  - Alaca R
AD  - Department of Child Psychiatry, Dicle University School of Medicine, Diyarbakir, 
      Turkey.
LA  - eng
PT  - Journal Article
DEP - 20161201
PL  - Turkey
TA  - Noro Psikiyatr Ars
JT  - Noro psikiyatri arsivi
JID - 9426194
PMC - PMC5353043
OTO - NOTNLM
OT  - Attention-deficit hyperactivity disorder
OT  - Stroop
OT  - brain-derived neurotropic factor
OT  - executive functions
OT  - pathophysiology
COIS- Conflict of Interest: No conflict of interest was declared by the authors.
EDAT- 2017/04/01 06:00
MHDA- 2017/04/01 06:01
PMCR- 2016/12/01
CRDT- 2017/04/01 06:00
PHST- 2015/02/13 00:00 [received]
PHST- 2015/09/05 00:00 [accepted]
PHST- 2017/04/01 06:00 [entrez]
PHST- 2017/04/01 06:00 [pubmed]
PHST- 2017/04/01 06:01 [medline]
PHST- 2016/12/01 00:00 [pmc-release]
AID - npa-53-4-348 [pii]
AID - 10.5152/npa.2016.10234 [doi]
PST - ppublish
SO  - Noro Psikiyatr Ars. 2016 Dec;53(4):348-352. doi: 10.5152/npa.2016.10234. Epub 
      2016 Dec 1.