PMID- 28361824 OWN - NLM STAT- MEDLINE DCOM- 20170721 LR - 20240325 IS - 0971-5916 (Print) IS - 0971-5916 (Linking) VI - 144 IP - 5 DP - 2016 Nov TI - Postprandial glycaemic response of foxtail millet dosa in comparison to a rice dosa in patients with type 2 diabetes. PG - 712-717 LID - 10.4103/ijmr.IJMR_551_15 [doi] AB - BACKGROUND & OBJECTIVES: Millets are rich source of dietary fibre and non-starchy polysaccharides with low glycaemic index (GI), hence can be used as a therapeutic diet. This study was conducted to estimate the effects of a millet-based dosa (foxtail dosa) compared to a rice dosa for breakfast on postprandial glucose levels in patients with type 2 diabetes mellitus (T2DM). METHODS: The GI of rice dosa and foxtail millet dosa was estimated. A total of 105 T2DM participants were randomly selected for the study. The participants were on oral hypoglycaemic agents (OHA) and not on insulin. In this study, each individual served as their own control and experimental group. The postprandial increase in blood glucose was compared after a breakfast of rice dosa and millet dosa. Single and paired t test was used to note the change in blood glucose levels and the level of the significance. RESULTS: The GI of foxtail millet dosa was 59.25 and rice dosa was 77.96. There was a significant reduction (P<0.001) in the postprandial glucose level of patients who consumed a millet-based dosa when compared to those who consumed a rice-based dosa. No significant reduction was observed in the fasting glucose levels. INTERPRETATION & CONCLUSIONS: The results suggested that replacing a rice-based breakfast item with a millet-based breakfast item lowers the postprandial blood glucose levels in T2DM patients. Thus, millets may have a protective role in the management of hyperglycaemia. Further studies need to be done in a systematic manner to confirm these findings. FAU - Narayanan, Janani AU - Narayanan J AD - M.V. Hospital for Diabetes & Prof M.Viswanathan Diabetes Research Centre (WHO Collaborating Centre for Research, Education and Training in Diabetes), Chennai, India. FAU - Sanjeevi, Vimala AU - Sanjeevi V AD - M.V. Hospital for Diabetes & Prof M.Viswanathan Diabetes Research Centre (WHO Collaborating Centre for Research, Education and Training in Diabetes), Chennai, India. FAU - Rohini, U AU - Rohini U AD - M.V. Hospital for Diabetes & Prof M.Viswanathan Diabetes Research Centre (WHO Collaborating Centre for Research, Education and Training in Diabetes), Chennai, India. FAU - Trueman, Patricia AU - Trueman P AD - M.V. Hospital for Diabetes & Prof M.Viswanathan Diabetes Research Centre (WHO Collaborating Centre for Research, Education and Training in Diabetes), Chennai, India. FAU - Viswanathan, Vijay AU - Viswanathan V AD - M.V. Hospital for Diabetes & Prof M.Viswanathan Diabetes Research Centre (WHO Collaborating Centre for Research, Education and Training in Diabetes), Chennai, India. LA - eng PT - Journal Article PL - India TA - Indian J Med Res JT - The Indian journal of medical research JID - 0374701 RN - 0 (Blood Glucose) SB - IM MH - Adult MH - Blood Glucose MH - Diabetes Mellitus, Type 2/blood/complications/*diet therapy MH - Dose-Response Relationship, Drug MH - Fasting MH - Female MH - Humans MH - Hyperglycemia/*blood/chemically induced/pathology MH - Male MH - Middle Aged MH - Oryza/*adverse effects MH - Setaria Plant/*adverse effects PMC - PMC5393082 COIS- Conflicts of Interest: None. EDAT- 2017/04/01 06:00 MHDA- 2017/07/22 06:00 PMCR- 2016/11/01 CRDT- 2017/04/01 06:00 PHST- 2017/04/01 06:00 [entrez] PHST- 2017/04/01 06:00 [pubmed] PHST- 2017/07/22 06:00 [medline] PHST- 2016/11/01 00:00 [pmc-release] AID - IndianJMedRes_2016_144_5_712_203460 [pii] AID - IJMR-144-712 [pii] AID - 10.4103/ijmr.IJMR_551_15 [doi] PST - ppublish SO - Indian J Med Res. 2016 Nov;144(5):712-717. doi: 10.4103/ijmr.IJMR_551_15.