PMID- 28366419 OWN - NLM STAT- MEDLINE DCOM- 20180620 LR - 20180709 IS - 1532-8430 (Electronic) IS - 0022-0736 (Linking) VI - 50 IP - 5 DP - 2017 Sep-Oct TI - An evaluation of planarity of the spatial QRS loop by three dimensional vectorcardiography: Its emergence and loss. PG - 652-660 LID - S0022-0736(17)30080-8 [pii] LID - 10.1016/j.jelectrocard.2017.03.016 [doi] AB - AIMS: To objectively characterize and mathematically justify the observation that vectorcardiographic QRS loops in normal individuals are more planar than those from patients with ST elevation myocardial infarction (STEMI). METHODS: Vectorcardiograms (VCGs) were constructed from three simultaneously recorded quasi-orthogonal leads, I, aVF and V(2) (sampled at 1000 samples/s). The planarity of these QRS loops was determined by fitting a surface to each loop. Goodness of fit was expressed in numerical terms. RESULTS: 15 healthy individuals aged 35-65years (73% male) and 15 patients aged 45-70years (80% male) with diagnosed acute STEMI were recruited. The spatial-QRS loop was found to lie in a plane in normal controls. In STEMI patients, this planarity was lost. Calculation of goodness of fit supported these visual observations. CONCLUSIONS: The degree of planarity of the VCG loop can differentiate healthy individuals from patients with STEMI. This observation is compatible with our basic understanding of the electrophysiology of the human heart. CI - Copyright (c) 2017 Elsevier Inc. All rights reserved. FAU - Ray, Dipanjan AU - Ray D AD - Dept. of Physiology, Calcutta Medical College, 88, College Street, Calcutta, India. FAU - Hazra, Sandipan AU - Hazra S AD - Dept. of General Medicine, RG Kar Medical College, 1, KhudiramBasuSarani, Calcutta, India. FAU - Goswami, Damodar Prasad AU - Goswami DP AD - Dept. of Mathematics, Narula Institute of Technology, 81, Nilgunj Road, Agarpara, West Bengal, India. FAU - Macfarlane, Peter W AU - Macfarlane PW AD - University of Glasgow, Inst of Health and Wellbeing, Electrocardiology Group, Royal Infirmary, Glasgow, G31 2ER, UK. FAU - Sengupta, Arnab AU - Sengupta A AD - Dept. of Physiology, Calcutta Medical College, 88, College Street, Calcutta, India. Electronic address: arnabseng@gmail.com. LA - eng PT - Journal Article DEP - 20170322 PL - United States TA - J Electrocardiol JT - Journal of electrocardiology JID - 0153605 SB - IM MH - Adult MH - Aged MH - Case-Control Studies MH - Female MH - Humans MH - Male MH - Middle Aged MH - ST Elevation Myocardial Infarction/*diagnosis MH - Vectorcardiography/*methods OTO - NOTNLM OT - Healthy controls OT - QRS plane OT - STEMI OT - Uniform double layer OT - Vectorcardiogram EDAT- 2017/04/04 06:00 MHDA- 2018/06/21 06:00 CRDT- 2017/04/04 06:00 PHST- 2016/11/19 00:00 [received] PHST- 2017/04/04 06:00 [pubmed] PHST- 2018/06/21 06:00 [medline] PHST- 2017/04/04 06:00 [entrez] AID - S0022-0736(17)30080-8 [pii] AID - 10.1016/j.jelectrocard.2017.03.016 [doi] PST - ppublish SO - J Electrocardiol. 2017 Sep-Oct;50(5):652-660. doi: 10.1016/j.jelectrocard.2017.03.016. Epub 2017 Mar 22.