PMID- 28367709 OWN - NLM STAT- MEDLINE DCOM- 20180430 LR - 20180430 IS - 1465-3478 (Electronic) IS - 0963-7486 (Linking) VI - 68 IP - 7 DP - 2017 Nov TI - The microbial fermentation characteristics depend on both carbohydrate source and heat processing: a model experiment with ileo-cannulated pigs. PG - 811-820 LID - 10.1080/09637486.2017.1307947 [doi] AB - The effects of carbohydrate (CHO) source and processing (extrusion cooking) on large intestinal fermentation products were studied in ileo-cannulated pigs as a model for humans. Pigs were fed diets containing barley, pea or a mixture of potato starch:wheat bran (PSWB) either raw or extrusion cooked. Extrusion cooking reduced the amount of starch fermented in the large intestine by 52-96% depending on the CHO source and the total pool of butyrate in the distal small intestine + large intestine by on average 60% across diets. Overall, extrusion cooking caused a shift in the composition of short-chain fatty acids (SCFA) produced towards more acetate and less propionate and butyrate. The CHO source and processing highly affected the fermentation characteristics and extrusion cooking generally reduced large intestinal fermentation and resulted in a less desirable composition of the fermentation products. The latter outcome is non-conducive to a healthy large intestinal environment and its resulting metabolic health. FAU - Nielsen, Tina Skau AU - Nielsen TS AD - a Department of Animal Science , Aarhus University , Tjele , Denmark. FAU - Jorgensen, Henry AU - Jorgensen H AD - a Department of Animal Science , Aarhus University , Tjele , Denmark. FAU - Knudsen, Knud Erik Bach AU - Knudsen KEB AD - a Department of Animal Science , Aarhus University , Tjele , Denmark. FAU - Laerke, Helle Nygaard AU - Laerke HN AD - a Department of Animal Science , Aarhus University , Tjele , Denmark. LA - eng PT - Journal Article DEP - 20170402 PL - England TA - Int J Food Sci Nutr JT - International journal of food sciences and nutrition JID - 9432922 RN - 0 (Carbohydrates) SB - IM MH - Animal Feed MH - Animal Nutritional Physiological Phenomena MH - Animals MH - Carbohydrates/*chemistry MH - Diet/veterinary MH - Edible Grain/*chemistry MH - *Food Handling MH - *Hot Temperature MH - Intestine, Large/metabolism/*microbiology MH - Male MH - Solanum tuberosum/chemistry MH - Swine/microbiology/*physiology OTO - NOTNLM OT - Starch OT - butyrate OT - dietary fibre OT - extrusion cooking OT - fermentation products EDAT- 2017/04/04 06:00 MHDA- 2018/05/01 06:00 CRDT- 2017/04/04 06:00 PHST- 2017/04/04 06:00 [pubmed] PHST- 2018/05/01 06:00 [medline] PHST- 2017/04/04 06:00 [entrez] AID - 10.1080/09637486.2017.1307947 [doi] PST - ppublish SO - Int J Food Sci Nutr. 2017 Nov;68(7):811-820. doi: 10.1080/09637486.2017.1307947. Epub 2017 Apr 2.